Clinimetric Properties of Performance Based Functional Outcome Measure After (CABG) Surgery

NCT07060937 | Recruiting DMC

• 1 other identifier: Zarish Ayub
• Study Type: interventional
• Target: 150
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this research is to determine which performance based functional outcome test among Time up and go test, Five times sit to stand test, 2 minute walk test and 6 minute walk test has the greatest significance in improving functional outcomes in post-CABG surgery patients.

Conditions

Coronary Artery Disease; CABG

Keywords

Clinimetric properties; Performance based functional outcomes; Time up and go test; Five times sit to stand test; 2 minute walk test; 6 minute walk test

Outcome Measures

Primary Outcomes (4)

• Time up and go test

  On post op- day 3 and 5 Participants will quickly perform test to assess lower extremity strength and risk of fall. The time taken to complete test will be noted

  6 hours

• Five times sit to stand test

  On post-op day 3 and 5, Participants will perform test by transitioning from sitting to standing five times in row, time would be noted. This test helps to evaluate lower extremity balance and strength.

  6 hours

• 2 Minute walk test

  The test will be performed on post-op day 3 and 5, the participants will walk on a flat surface in a straight line and the distance will be noted. This test assess endurance

  6 hours

• 6 Minute walk test

  This is a self-paced test which will be performed on post-op day 3 and 5 where the participants have walk on a flat, smooth surface. The distance covered during this test will be noted. It measures aerobic capacity and endurance.

  6 hours

Study Arms (1)

Post CABG surgery patients

EXPERIMENTAL

The intervention includes 30-50 years old male and female post-CABG surgery patients. They will be recruited according to the inclusion criteria of the study and all baseline measurements will be taken from each participant to ensure readiness for the tests performed. The participants will undergo functionality based performance tests which include 5 Time sit to stand test, Time up and go test, 2 Minute walk test and 6 Minute walk test on post-op day 3 and day 5 respectively. The test will be performed twice on post-op day 3 and post-op day 5 with 6 hours minimum gap in between to promote patient recovery and test re-test reliability. Participants pre-test and post-test vitals will be taken and their test outcomes readings will be noted on the self-administered questionnaire.

Other: Physiotherapy Protocol

Interventions

Physiotherapy Protocol OTHER

Each participant consenting to the study will be given a physiotherapy session on post-op day 1 and day 2 by a physiotherapist. The session will include bed mobility exercises including active ROM exercises of all extremities, breathing exercises, nebulization and chest physical therapy, incentive spirometer. Progressing to supported sitting at the edge of bed, sitting on a chair under supervision, supported walk inside the room , sitting independently in chair and lastly before discharge climbing 2 flights of stair.

Post CABG surgery patients

Eligibility Criteria

• Age: 30 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• years old
• Post-op CABG patients
• Include male and female both
• Mobile patients
• Post-op day 3 and day 5 of CABG surgery

You may not qualify if:

• Occurrence of adverse events
• Unstable hemodynamically
• Patients with documented cognitive dysfunction
• Patients with neurologic or musculoskeletal disease (excluding osteoarthritis) that adversely affects gait or weight-bearing
• Patients with severe co-morbidities, recurrent attacks, and unstable condition.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (2)

Armed Forces Institute of Cardiology

Rawalpindi, Punjab Province, 44000, Pakistan

RECRUITING

Armed Forces Institute of Cardiology

Rawalpindi, Punjab Province, 46000, Pakistan

NOT YET RECRUITING

Related Publications (7)

• Melo TA, Duarte ACM, Bezerra TS, Franca F, Soares NS, Brito D. The Five Times Sit-to-Stand Test: safety and reliability with older intensive care unit patients at discharge. Rev Bras Ter Intensiva. 2019;31(1):27-33. doi: 10.5935/0103-507X.20190006. Epub 2019 Mar 14.

  PMID: 30892478 BACKGROUND

• Rodrigues F, Teixeira JE, Forte P. The Reliability of the Timed Up and Go Test among Portuguese Elderly. Healthcare (Basel). 2023 Mar 23;11(7):928. doi: 10.3390/healthcare11070928.

  PMID: 37046858 BACKGROUND

• de Jesus SFC, Bassi-Dibai D, Pontes-Silva A, da Silva de Araujo A, de Freitas Faria Silva S, Veneroso CE, de Paula Gomes CAF, Dibai-Filho AV. Construct validity and reliability of the 2-Minute Step Test (2MST) in individuals with low back pain. BMC Musculoskelet Disord. 2022 Dec 5;23(1):1062. doi: 10.1186/s12891-022-06050-w.

  PMID: 36471309 BACKGROUND

• Giannitsi S, Bougiakli M, Bechlioulis A, Kotsia A, Michalis LK, Naka KK. 6-minute walking test: a useful tool in the management of heart failure patients. Ther Adv Cardiovasc Dis. 2019 Jan-Dec;13:1753944719870084. doi: 10.1177/1753944719870084.

  PMID: 31441375 BACKGROUND

• Essop-Adam A, Daynes E, Houghton JSM, Nickinson ATO, Sayers RDS, Haunton VJ, Pepper C, Singh SJ. Clinimetrics of performance-based functional outcome measures for vascular amputees: A systematic review. Ann Phys Rehabil Med. 2023 Sep;66(6):101756. doi: 10.1016/j.rehab.2023.101756. Epub 2023 Jun 3.

  PMID: 37276748 BACKGROUND

• Osailan A, Abdelbasset WK. Exercise-based cardiac rehabilitation for postcoronary artery bypass grafting and its effect on hemodynamic responses and functional capacity evaluated using the Incremental Shuttle Walking Test: A retrospective pilot analysis. J Saudi Heart Assoc. 2020 Apr 17;32(1):25-33. doi: 10.37616/2212-5043.1005. eCollection 2020.

  PMID: 33154888 BACKGROUND

• Puri SN, Lalwani L. A Comparison Between Cardiac Telerehabilitation Program and Outpatient Hospital-Based Cardiac Rehabilitation Program for Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery: A Review. Cureus. 2023 Nov 8;15(11):e48488. doi: 10.7759/cureus.48488. eCollection 2023 Nov.

  PMID: 38073989 BACKGROUND

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Suman Sheraz, PhD

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Suman Sheraz, PhD

CONTACT

923335646361; suman.sheraz@riphah.edu.pk

Imran Amjad, PhD

CONTACT

923324390125; imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 11, 2025
• Study Start: December 10, 2025
• Primary Completion: March 30, 2026
• Study Completion: April 15, 2026
• Last Updated: January 5, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

PA (2)