Illness Perception and Quality of Life in Colorectal Cancer With Ascites

NCT07059052 | Completed

• 1 other identifier: 2024021
• Study Type: observational
• Target: 218
• Locations: 1 country
• Sites: 1

Brief Summary

This study aimed to investigate the impact of illness perception on the quality of life (QoL) in patients diagnosed with colorectal cancer (CRC) complicated by ascites. The study explores how patients' cognitive and emotional beliefs about their illness relate to their physical, psychological, and social well-being.

Conditions

Colorectal Cancer (MSI-H)

Keywords

Illness Perception; Colorectal Cancer with Ascites; Quality of Life; Age; Histological Grade

Outcome Measures

Primary Outcomes (2)

• Quality of Life Score

  Assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30, version 3.0). This 30-item questionnaire evaluates global health status, five functional scales (physical, role, emotional, cognitive, social), and symptom scales. All scores are transformed to a 0-100 scale. For functional scales and global QoL, higher scores represent better functioning or QoL.

  Assessed once per participant during the study period from January 2024 to April 2025

• Illness Perception Score

  Assessed using the Brief Illness Perception Questionnaire (BIPQ). This 8-item questionnaire evaluates cognitive and emotional representations of illness on a 0-10 scale. The total score ranges from 0 to 80, with higher scores indicating a more threatening or negative illness perception after reverse-scoring relevant items.

  Assessed once per participant during the study period from January 2024 to April 2025

Study Arms (1)

Patients with Colorectal Cancer and Ascites

A single cohort of 218 patients with a confirmed diagnosis of colorectal cancer and concomitant ascites. These patients were treated at the Hebei Provincial Hospital of Traditional Chinese Medicine between January 2024 and April 2025. Data on their clinical characteristics, illness perceptions, and quality of life were collected at a single point in time for this cross-sectional analysis.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population included patients diagnosed with colorectal cancer and concomitant ascites. Participants were recruited from those treated at the Hebei Provincial Hospital of Traditional Chinese Medicine between January 2024 and April 2025. All consecutive patients who met the specific inclusion and exclusion criteria during this period and provided informed consent were enrolled in this cross-sectional study.

You may qualify if:

• Confirmed diagnosis of colorectal cancer with ascites, verified by imaging and pathological examination.
• Patient and/or legal guardian provided informed consent.
• Karnofsky Performance Status (KPS) score ≥50.
• Estimated survival ≥6 months.

You may not qualify if:

• Presence of other active malignant tumors.
• Severe physical disability precluding participation.
• Severe cardiac, hepatic, or renal dysfunction not related to CRC.
• Presence of severe psychiatric or cognitive disorders.
• History of alcohol or drug addiction.

Sponsors & Collaborators

• Hebei Provincial Hospital of Traditional Chinese Medicine: lead

Study Sites (1)

Hebei Provincial Hospital of Traditional Chinese Medicine

Shijiazhuang, Hebei, 050000, China

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 3 Months
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 1, 2025
• First Posted: July 10, 2025
• Study Start: January 1, 2024
• Primary Completion: April 30, 2025
• Study Completion: April 30, 2025
• Last Updated: July 10, 2025

Record last verified: 2025-07

Locations

CN (1)