Is Pericapsular Nerve Group Block Better Than Interscalene Nerve Block Regarding Effect on Hand Movement in Shoulder Scope Surgeries?

NCT07057947 | Recruiting DMC

• 1 other identifier: MD-323-2024
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to learn if pericapsular nerve group block (PENG) in shoulder scope surgery provides adequate analgesia with less affection of muscle power compared to interscalene block. The main questions it aims to answer are: Does PENG block provide analgesia similar to interscalene block? Does PENG block have less or no effect on muscle power compared to interscalene block? Researchers will compare PENG block with interscalene block Participants will: Receive either PENG or interscalene block before shoulder scope surgery Be evaluated for their motor power after receiving the block and after the surgery Be evaluated for pain after the surgery

Conditions

Shoulder Arthroscopic Surgery

Outcome Measures

Primary Outcomes (1)

• Time for full recovery of hand motor power

  Time from start of block activation till time of achieving grip strength similar to patient's baseline

  Starting from block activation until the achieves preoperative grip strength ( 24 hours)

Secondary Outcomes (4)

• Hand grip power after surgery

  2,4,6,12,24 hours

• Visual analogue scale assessment

  2,4,6,12 hours

• Time to first analgesia request

  24 hours

• Patient satisfaction score

  24 hours

Study Arms (2)

Group P

ACTIVE COMPARATOR

This arm will receive PENG block

Procedure: Pericapsular Nerve Group (PENG) Block; Device: Acuson X300 ultrasound,Siemens medical solution INC, Germany

Group I

ACTIVE COMPARATOR

This arm will receive interscalene block

Procedure: Interscalene Nerve Block; Device: Acuson X300 ultrasound,Siemens medical solution INC, Germany

Interventions

Pericapsular Nerve Group (PENG) Block PROCEDURE

Injection of local anesthetic between deltoid muscle and subcapsularis tendon

Group P

Interscalene Nerve Block PROCEDURE

Injection of local anesthetic between anterior and middle scalene muscles around the roots of brachial plexus

Group I

Acuson X300 ultrasound,Siemens medical solution INC, Germany DEVICE

high frequency linear probe

Group I; Group P

Eligibility Criteria

• Age: 22 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Adult patients of the specified age range
• Any gender
• American Society of Anaesthesiologists physical status grades 1 and 2
• Body mass index less than 35
• Duration of surgery between 90 to 120 minutes

You may not qualify if:

• American Society of Anaesthesiologists physical status grades 3 and 4
• Allergy to local anesthetics
• Coagulation disorder (INR \>1.2, Platelets \<100,000), or recent intake of clopidogrel or warfarin within 1 week
• Active infection at site of injection

Sponsors & Collaborators

• Sherin Refaat: lead

Study Sites (1)

Cairo University

Cairo, 11562, Egypt

RECRUITING

Related Publications (11)

• Mosaffa F, Taheri M, Manafi Rasi A, Samadpour H, Memary E, Mirkheshti A. Comparison of pericapsular nerve group (PENG) block with fascia iliaca compartment block (FICB) for pain control in hip fractures: A double-blind prospective randomized controlled clinical trial. Orthop Traumatol Surg Res. 2022 Feb;108(1):103135. doi: 10.1016/j.otsr.2021.103135. Epub 2021 Oct 29.

  PMID: 34715388 BACKGROUND

• Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.

  PMID: 30063657 BACKGROUND

• Kupeli I, Yazici Kara M. Anesthesia or analgesia? New block for shoulder surgery: pericapsular nerve group block. Braz J Anesthesiol. 2022 Sep-Oct;72(5):669-672. doi: 10.1016/j.bjane.2021.05.009. Epub 2021 Jun 9.

  PMID: 34118263 BACKGROUND

• Hussain N, Goldar G, Ragina N, Banfield L, Laffey JG, Abdallah FW. Suprascapular and Interscalene Nerve Block for Shoulder Surgery: A Systematic Review and Meta-analysis. Anesthesiology. 2017 Dec;127(6):998-1013. doi: 10.1097/ALN.0000000000001894.

  PMID: 28968280 BACKGROUND

• Stasiowski M, Zuber M, Marciniak R, Kolny M, Chabierska E, Jalowiecki P, Pluta A, Missir A. Risk factors for the development of Horner's syndrome following interscalene brachial plexus block using ropivacaine for shoulder arthroscopy: a randomised trial. Anaesthesiol Intensive Ther. 2018;50(3):215-220. doi: 10.5603/AIT.a2018.0013. Epub 2018 Jun 22.

  PMID: 29931665 BACKGROUND

• Bergmann L, Martini S, Kesselmeier M, Armbruster W, Notheisen T, Adamzik M, Eichholz R. Phrenic nerve block caused by interscalene brachial plexus block: breathing effects of different sites of injection. BMC Anesthesiol. 2016 Jul 29;16(1):45. doi: 10.1186/s12871-016-0218-x.

  PMID: 27473162 BACKGROUND

• Paul RW, Szukics PF, Brutico J, Tjoumakaris FP, Freedman KB. Postoperative Multimodal Pain Management and Opioid Consumption in Arthroscopy Clinical Trials: A Systematic Review. Arthrosc Sports Med Rehabil. 2021 Dec 17;4(2):e721-e746. doi: 10.1016/j.asmr.2021.09.011. eCollection 2022 Apr.

  PMID: 35494281 BACKGROUND

• Guity MR, Sobhani Eraghi A, Hosseini-Baharanchi FS. Early postoperative pain as a risk factor of shoulder stiffness after arthroscopic rotator cuff repair. J Orthop Traumatol. 2021 Jun 26;22(1):25. doi: 10.1186/s10195-021-00585-9.

  PMID: 34173872 BACKGROUND

• Calvo E, Torres MD, Morcillo D, Leal V. Rotator cuff repair is more painful than other arthroscopic shoulder procedures. Arch Orthop Trauma Surg. 2019 May;139(5):669-674. doi: 10.1007/s00402-018-3100-0. Epub 2018 Dec 17.

  PMID: 30560289 BACKGROUND

• Zong LZ, Duan MM, Yuan WW, Lu HD. Efficacy of shoulder arthroscopic surgery for the treatment of rotator cuff injury: A protocol of systematic review and meta-analysis. Medicine (Baltimore). 2020 Jun 26;99(26):e20591. doi: 10.1097/MD.0000000000020591.

  PMID: 32590734 BACKGROUND

• Farmer KW, Wright TW. Shoulder arthroscopy: the basics. J Hand Surg Am. 2015 Apr;40(4):817-21. doi: 10.1016/j.jhsa.2015.01.002. Epub 2015 Feb 26.

  PMID: 25726045 BACKGROUND

MeSH Terms

Interventions

Dental Occlusion

Intervention Hierarchy (Ancestors)

Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena

Central Study Contacts

Research Ethics Committee

CONTACT

+201112137888; kasralainyrec@kasralainy.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Dr. Sherine Refaat Mahmoud, Assistant Professor of anesthesiology, surgical ICU and pain management

Study Record Dates

• First Submitted: March 11, 2025
• First Posted: July 10, 2025
• Study Start: August 25, 2025
• Primary Completion: September 1, 2025
• Study Completion: December 1, 2025
• Last Updated: July 14, 2025

Record last verified: 2025-07

Locations

EG (1)