NCT07057076|Completed
Microbiome and Colorectal Cancer Recurrence
The Role of Microbiome in Recurrence After Colorectal Cancer Surgery With Postoperative Organ/Space Surgical Site Infection
Loading search results
The Role of Microbiome in Recurrence After Colorectal Cancer Surgery With Postoperative Organ/Space Surgical Site Infection
Sponsor study identifier
Secondary identifiers
OTHER_GRANT · Institute of Health Carlos III
OTHER_GRANT · Agency for Management of University and Research Grants (AGAUR)
observational
51
0 countries
N/A
Study Start
January 1, 2004
Actual (reported)Primary Completion
June 1, 2024
Actual (reported)Study Completion
June 1, 2024
Actual (reported)Anastomotic leak is associated with higher rates of tumor recurrence after colorectal cancer surgery. However, the mechanisms responsible remain unknown. The aim of this study is to identify associations between the peritoneal microbiome and recurrence in colorectal cancer patients with postoperative anastomotic leak. This is a single-center retrospective study of patients undergoing colorectal cancer surgery complicated with anastomotic leak between 2004 and 2012. Samples of peritoneal fluid were collected either through percutaneous drainage or reoperation, and microbiome was analyzed using whole genome shotgun. Oncological outcomes are registered. Associations between peritoneal microbiome and tumor recurrence are investigated.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 1, 2024
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2004
Actual (reported)June 1, 2024
Actual (reported)June 1, 2024
Actual (reported)June 29, 2025
Actual (reported)July 9, 2025
Actual (reported)Recurrence
Colorectal cancer recurrence after surgery
5 years
Colorectal cancer patients operated on for cure and complicated by anastomotic leak
Colorectal cancer patients operated on for cure and complicated with anastomotic leak.
Peritoneal fluid
51 participants (actual enrollment reported by the registry).
First Submitted
June 29, 2025
First Posted
July 9, 2025
Study Start
January 1, 2004
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
June 1, 2024
Actual (reported)Study Completion
June 1, 2024
Actual (reported)Last Updated
July 9, 2025
Record last verified: 2025-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: