Correlation Between Coagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan

NCT07051395 | Active Not Recruiting DMC

• 1 other identifier: MSAHSW/Batch-Fall23/922
• Study Type: observational
• Target: 230
• Locations: 1 country
• Sites: 1

Brief Summary

Trauma-induced coagulopathy (TIC), also known as acute traumatic coagulopathy (ATC), is a common condition in patients with severe trauma, particularly in road traffic accident (RTA) victims. Coagulopathy is often associated with high mortality rates and poor outcomes in trauma patients.

Conditions

Accident, Traffic

Outcome Measures

Primary Outcomes (1)

• Self Admisnistred questioner

  A Self Admisnistred questioner is used to collect the data and details of the accident

  12 Months

Interventions

Road Traffic Accidents Patient DIAGNOSTIC_TEST

Coagulation Profiles And Injury Severity In Road Traffic Accidents Patients at Dera Ismail Khan

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

To assess the correlation between coagulation profiles and injury severity in trauma patients, with a focus on the prevalence of trauma-induced coagulopathy (TIC) in road traffic accident (RTA) cases at a tertiary care hospital in Dera Ismail Khan. Methods: A cross-sectional observational study will be conducted in the Accident \& Emergency (A\&E) Department and Trauma Center of DHQ Hospital, Dera Ismail Khan. The study population includes patients aged 18 years and above, with moderate to severe injuries (Injury Severity Score ≥ 15),

You may qualify if:

• Patients with moderate to severe injuries (Injury Severity Score\>15).
• All Patients will be admitted in Accident and Emergency Center after the accident.

You may not qualify if:

• Patients with Mild injury and score \<15.
• Patients with pre-existing coagulation disorders (e.g., hemophilia).
• Patients on anticoagulant therapy prior to admission.
• Patients with incomplete medical records or insufficient blood samples.

Sponsors & Collaborators

• Superior University: lead

Study Sites (1)

Mufti Mehmood Memorial Teaching Hospital

Dera Ismāīl Khān, Khyber Pakhtunkhwa, Pakistan

Location

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 26, 2025
• First Posted: July 4, 2025
• Study Start: March 17, 2025
• Primary Completion: September 1, 2025
• Study Completion: March 1, 2026
• Last Updated: July 4, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)