Evaluating the Diagnostic Performance of (HRCT) in IPD Fibrosis in Suspected Cases

NCT07048652 | Active Not Recruiting DMC

• 1 other identifier: MSAHSW/Batch-Fall23/905
• Study Type: observational
• Target: 68
• Locations: 1 country
• Sites: 1

Brief Summary

This will be a cross-sectional descriptive study aimed at evaluating the role of high-resolution computed tomography (HRCT) in diagnosing Idiopathic Pulmonary Fibrosis (IPF).

Conditions

Idiopathic Pulmonary Fibrosis

Outcome Measures

Primary Outcomes (1)

• high-resolution computed tomography (HRCT)

  Idiopathic Pulmonary Fibrosis (IPF) high-resolution computed tomography (HRCT) scans are crucial for diagnosis and assessment of disease severity. HRCT findings typically show a reticular pattern with traction bronchiectasis and honeycombing, predominantly in the subpleural and basal regions of the lungs

  12 Months

Interventions

High-Resolution Computed Tomography DIAGNOSTIC_TEST

High-resolution computed tomography (HRCT) plays a crucial role in diagnosing and managing Idiopathic Pulmonary Fibrosis (IPF). It helps identify the characteristic pattern of IPF, known as Usual Interstitial Pneumonia (UIP), and can sometimes obviate the need for lung biopsy.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Idiopathic Pulmonary Fibrosis (IPF): IPF is defined as a chronic, progressive fibrotic interstitial lung disease diagnosed based on clinical evaluation, exclusion of other potential causes, and characteristic radiological findings on high-resolution CT (HRCT).

You may qualify if:

• Patients aged 18 years and above.
• Patients clinically suspected of having IPF.
• Patients referred for HRCT examination.
• Patients who provide informed consent to participate in the study.

You may not qualify if:

• Patients with a known diagnosis of other interstitial lung diseases.
• Patients with comorbid conditions that could mimic IPF.
• Patients who are pregnant.
• Patients with incomplete medical records or imaging studies

Sponsors & Collaborators

• Superior University: lead

Study Sites (1)

AYK Hospital

Lahore, Pakistan

Location

MeSH Terms

Conditions

Idiopathic Pulmonary Fibrosis

Condition Hierarchy (Ancestors)

Pulmonary Fibrosis; Lung Diseases, Interstitial; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 24, 2025
• First Posted: July 2, 2025
• Study Start: March 17, 2025
• Primary Completion: September 1, 2025
• Study Completion: February 28, 2026
• Last Updated: July 2, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)