Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis

NCT07046533 | Not Yet Recruiting DMC

• 1 other identifier: Cairo2007
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first permanent molars with irreversible pulpitis.

Conditions

Irreversible Pulpitis (Toothache); Dental Caries (Diagnosis)

Keywords

randomized control trial; vital pulp therapy

Outcome Measures

Primary Outcomes (1)

• success rate

  clinically and radiographically success rate according to success criteria

  12 months

Study Arms (2)

root canal treatment

ACTIVE COMPARATOR

invasive technique depends on removal of all pulp tissue coronal and radicular and restore it with a gutta perch with bioceramic sealer

Procedure: (pulpotomy); Procedure: root canal treatment

pulpotomy

EXPERIMENTAL

non invasive technique depends on removal of only coronal pulp tissue and restore it with a new material bio c repair

Procedure: (pulpotomy); Procedure: root canal treatment

Interventions

(pulpotomy) PROCEDURE

non invasive technique depends on remove only the coronal pulp tissue instead of remove all pulp tissue

Also known as: vital pulp therapy

pulpotomy; root canal treatment

root canal treatment PROCEDURE

invasive technique depends on remove all radicular and coronal pulp tissue

pulpotomy; root canal treatment

Eligibility Criteria

• Age: 9 Months - 14 Months
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Molars teeth with a history of spontaneous radiating pain indicated IP
• the pain triggered by hot/cold fluids lasted for several minutes after removing of the stimulus.
• Molars teeth with no prominent radiolucency at the periapical or furcation regions

You may not qualify if:

• Teeth with continuous bleeding
• necrosis
• Teeth could not be restored with direct restoration. Teeth having localized/generalized periodontal diseases (probing pocket depth more than 3 mm).
• Teeth with crack fracture. Teeth with internal/external root resorption. Teeth with pulp chamber/canal calcification

Sponsors & Collaborators

• Lamiaa Saeed Ahmed Elshiekh: lead

MeSH Terms

Conditions

Toothache; Dental Caries; Disease

Interventions

Pulpotomy

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases; Facial Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Tooth Demineralization; Pathologic Processes

Intervention Hierarchy (Ancestors)

Endodontics; Dentistry

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Lecturer of Pediatric Dentistry, Faculty of Dentistry October 6th University

Study Record Dates

• First Submitted: June 13, 2025
• First Posted: July 1, 2025
• Study Start: July 1, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: July 1, 2025

Record last verified: 2025-06