TIPS Block vs. IV Analgesia for Postoperative Pain After Knee Arthroscopy

NCT07046390 | Not Yet Recruiting DMC

• 1 other identifier: FMASU MD24/2024
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

In this study participants are aiming to compare triple injection peri-sartorius (TIPS) block versus intravenous analgesia for postoperative analgesia after knee arthroscopy regarding efficacy of pain relief and early ambulation

Conditions

Knee Arthroscopic Surgery; Nerve Block

Outcome Measures

Primary Outcomes (1)

• postoperative analgesics

  24 hours postoperative

Secondary Outcomes (1)

• The secondary outcomes will be the total morphine consumption in mg , ambulation distances during the first 24 hours postoperative in meters

  24 hours postoperative

Study Arms (2)

tips block group

ACTIVE COMPARATOR

this group will receive triple injection peri-sartorius (TIPS) block. The block will be done after induction of general anesthesia before skin incision

Drug: nerve block with bupivacaine 0.25%; Drug: No intervention

control group

NO INTERVENTION

control group will receive conventional analgesic regimen without having a regional block.

Interventions

nerve block with bupivacaine 0.25% DRUG

0.25% bupivacaine

tips block group

No intervention DRUG

No intervention

tips block group

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-40 years undergoing knee arthroscopy. .Sex: Both sexes.
• American Society of Anaesthesiologists (ASA) Physical Status Class I and II

You may not qualify if:

• Declining to give written informed consent. .History of allergy to the medications used in the study. .Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).
• Psychiatric disorder. .American Society of Anesthesiologists (ASA) Physical Status Class III and IV.
• Patients with body mass index (BMI) \>35 kg/m2 .Neurological deficits or mobility-related disorders of the non-operated limb .
• Moderate to severe hepatic , renal diseases and cardiac disease.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Egypt

Location

MeSH Terms

Interventions

Nerve Block

Intervention Hierarchy (Ancestors)

Anesthesia, Conduction; Anesthesia; Anesthesia and Analgesia; Denervation; Neurosurgical Procedures; Surgical Procedures, Operative

Central Study Contacts

abdelrahman mohammed hanafy, master

CONTACT

01114359788; abdelrhmanhanafy@med.asu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 6, 2025
• First Posted: July 1, 2025
• Study Start: July 20, 2025
• Primary Completion (Estimated): July 20, 2026
• Study Completion (Estimated): August 20, 2026
• Last Updated: July 1, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)