The Role of Dysfunctional Schemas and Acceptance Regarding Chronic Fatigue in Oncology Patients After Treatment

NCT07042607 | Completed DMC

• 1 other identifier: METCZ20220084
• Study Type: observational
• Target: 118
• Locations: 1 country
• Sites: 1

Brief Summary

The role of dysfunctional schemas and acceptance regarding chronic fatigue in oncology patients after treatment This scientific cross-sectional study is at the intersection of medical psychology and oncology and will address the role of dysfunctional schemas and acceptance in the development of fatigue symptoms after treatment for cancer.

Conditions

Chronic Fatigue

Keywords

dysfunctional schema; acceptance; chronic fatigue

Outcome Measures

Primary Outcomes (3)

• Fatigue

  The Individual Stress Strength Checklist measures subjective fatigue and behavioral aspects related to it. It consists of 20 statements that examine how the respondent has felt over the past two weeks, indicating to what extent the statement applies to him/her. It measures a picture of fatigue that includes fluctuations over time. Four subscales are distinguished. The scoring method is on a 7-point Likert scale. A cut-off point for the total score is 76, indicating problematic fatigue. For the subjective fatigue subcategory, Normal = a score below 27. A score of 27 or higher is an indication of abnormal fatigue. A score of 35 or higher is considered an indication of severe fatigue.

  Baseline

• Dysfunctional schema

  The Young Schema Questionnaire-S3 (YSQ-S3) provides insight into dysfunctional schemas that may be underlying patients' psychological problems. The YSQ-S3 consists of 90 items (statements) measuring 18 schemas including the dysfunctional schemas of ruthless standards/excessive demands, self-sacrifice and abandonment. The method of scoring is on a 6-point Likert scale. After taking the YSQ-S3, the average of all scores per scale is calculated for high predictive value. For most schema scales, a mean score of 2.5 or higher usually appears to fall in the clinical range. The cut-off value for Self-sacrifice and Compassionate norms/extreme demands is around a mean of 3. Internal consistency is adequate for all 18 scales: Cronbach's α=0.70

  Baseline

• Acceptance

  The Freiburg mindfulness Inventory-Short Form (FMI-SF) is a questionnaire consisting of two subscales: Presence (attention to experiences of the present moment) and Acceptance (an accepting attitude toward experiences). The FMI-SF has the advantage of being a short list of 14 questions that can be applied in a clinical setting. The items can be scored from 1 (rarely) to 4 (almost always). Both the FMI-14 as a whole (Cronbach's α = .85) and the factors Presence (Cronbach's α= .74) have adequate internal consistency, providing support for the reliability of the scale and subscales.

  Baseline

Study Arms (1)

not appicable

not appicable

Other: not appicable

Interventions

not appicable OTHER

no intervention

not appicable

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All oncology patients (18 up to and including 70 years of age), at least 6 months to no later than five years after the last curative treatment and have had no other oncology treatment thereafter (except hormone therapy)

You may qualify if:

• All oncology patients (18 up to and including 70 years of age ), at least 6 months to no later than five years after the last curative treatment and have had no other oncology treatment thereafter (except hormone therapy). The type of oncology treatment (chemotherapy, radiotherapy, immunotherapy or hormone therapy) and the type of cancer they have had are diverse. Subjects recruited should have a good command of the Dutch language in connection with optimal reading and answering of the questionnaires.

Sponsors & Collaborators

• Zuyderland Medisch Centrum: lead

Study Sites (1)

Marianne van der Zijden

Heerlen, Limburg, 6438 HH, Netherlands

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: drs

Study Record Dates

• First Submitted: August 19, 2024
• First Posted: June 29, 2025
• Study Start: January 17, 2023
• Primary Completion: July 1, 2025
• Study Completion: July 31, 2025
• Last Updated: August 28, 2025

Record last verified: 2025-08

Locations

NL (1)