Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore.

NCT07042061 | Not Yet Recruiting

• 1 other identifier: ECOS 2024-3485
• Study Type: interventional
• Target: 1,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this clinical trial is to learn the feasibility of equipping the volunteer community responders (VCR) with the mobile external automated defibrillators (mAEDs) for the management of adults experiencing out-of-hospital cardiac arrest (OHCA) patients. It will also provide early signals if this enhanced system can help increase the frequency of defibrillation and doing it earlier. The main questions it aims to answer are:

• Can equipped VCRs apply mAEDs more frequently and earlier to potentially get more patients successfully resuscitated?
• Is this system enhancement is feasible in the long run. Participants, the VCRs, will:
• Carry a 450 gm mAED with them all the time for up to an year and use it on an OHCA patient if and when alerted to help.
• They will hand over this single-use battery-operated device to the EMS crew for data retrieval and potential replacement
• They will be interviewed for their experience of being equipped and use of the mAED.

Conditions

Out-of-hospital Cardiac Arrest (OHCA)

Keywords

Out-of-hospital; Cardiac arrest; Automated external defibrillator; AED; Community volunteers

Outcome Measures

Primary Outcomes (1)

• Feasibility of a full scale trial

  A validated AIM/FIM tool will be used to collect perceptions of the users and managers using a likert scale measurement reporting on feasibility and acceptability of the intervention

  Through study completion, an average of 1 year

Secondary Outcomes (3)

• Qualitative experiences of CFR elicited through semi-structured interviews

  1 year

• Qualitative experiences of CFR elicited through semi-structured interviews

  1 year

• Qualitative experiences of CFR elicited through semi-structured interviews

  1 year

Other Outcomes (3)

• Exploratory outcome mesaures

  1 year

• Exploratory outcome mesaures

  1 year

• Exploratory outcome mesaures

  1 year

Study Arms (1)

AED arm

EXPERIMENTAL

Device: Mobile external automated defibrillator

Interventions

Mobile external automated defibrillator DEVICE

A single-use, hand-held, chocolate bar sized portable AED

AED arm

Eligibility Criteria

• Age: 21 Years - 74 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Must be proficient in English. Able to read and understand English fluently.
• Be aged 21-74 years of age at point of recruitment.
• Willing and able to move rapidly to a scene that can be 400 meters away from their location.
• Be a registered CFR with SCDF.
• Must be active myResponder® mobile phone app user so they can receive alerts about nearby OHCA cases.

You may not qualify if:

• Not proficient in English. Cannot read and understand English.
• Aged less than 21 and over 74 years of age.
• Not willing to be a myResponder app user.
• Not able to move rapidly to a scene that can be 400 meters away from their location.
• Given the short duration of the trial, those who are pregnant will be ineligible.
• Those experiencing any serious physical injury or handicap and those with obvious mental handicap.

Sponsors & Collaborators

• Singapore General Hospital: lead
• Singapore Civil Defence Force: collaborator
• Duke-NUS Graduate Medical School: collaborator

Related Publications (1)

• Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.

  PMID: 28851459 BACKGROUND

MeSH Terms

Conditions

Out-of-Hospital Cardiac Arrest; Heart Arrest

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Central Study Contacts

Fahad J Siddiqui

CONTACT

+65 66017951; fahad.siddiqui@duke-nus.edu.sg

Garion Senior Executive

CONTACT

garion.koh@nus.edu.sg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 4, 2025
• First Posted: June 27, 2025
• Study Start: May 1, 2026
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): January 31, 2027
• Last Updated: April 27, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share