NCT07037563

Brief Summary

The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate its effectiveness in answering medication-related questions. The main questions it aims to answer are:

  1. 1.How satisfied are the patients and caregivers with this pharmacy chatbot?
  2. 2.How will the pharmacy chatbot impact eligible patients or caregivers on their (or the patient they are caring for) medication adherence, knowledge, and the consultation time with HA pharmacists?
  3. 3.The intervention group will be invited to use the AI Pharmacy Chatbot online for 7 days through WhatsApp, a commonly used social media platform in Hong Kong. They can inquire about their medications prescribed under HA and get instant, validated answers from the chatbot.
  4. 4.The control group will not use the chatbot during the intervention period.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
280

participants targeted

Target at P75+ for not_applicable

Timeline
6mo left

Started Jun 2025

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress66%
Jun 2025Oct 2026

Study Start

First participant enrolled

June 1, 2025

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

June 17, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 25, 2025

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2026

Last Updated

June 25, 2025

Status Verified

June 1, 2025

Enrollment Period

1.4 years

First QC Date

June 17, 2025

Last Update Submit

June 17, 2025

Conditions

Keywords

ChatbotIntelligent Conversational AgentArtificial IntelligenceImplementation Science

Outcome Measures

Primary Outcomes (2)

  • Medical knowledge

    Before the intervention period, all participants will be asked whether they disagree or agree with the following statements on a 5-point Likert scale (Strongly agree, Agree, Neutral, Disagree and Strongly disagree): 1. I understand the main indications of my medications (or the medications of the patient I care for). 2. I understand the potential side effects of my medications (or the medications of the patient I care for). 3. I know how to take my medications (or administer the medications of the patient I care), including the dosage and frequency, thereby promoting my medication adherence. 4. I have concerns or worries about my medications (or the medications of the patient I care for). 5. I can obtain medication-related information efficiently and easily. After the 7-day intervention period, they will be asked again the same questions.

    1 week

  • Medical adherence

    Before the intervention period, all participants will be asked whether they disagree or agree with the following statement on a 5-point Likert scale (Strongly agree, Agree, Neutral, Disagree and Strongly disagree): I know how to take my medications (or administer the medications of the patient I care), including the dosage and frequency, thereby promoting my medication adherence. After the 7-day intervention period, they will be asked again the same questions.

    1 week

Secondary Outcomes (3)

  • Response time

    1 week

  • User satisfaction

    1 week

  • Consultation with pharmacists

    1 week

Study Arms (2)

Pharmacy chatbot intervention group

EXPERIMENTAL

In this arm, participants will receive a pharmacy chatbot intervention. They will be invited to use the chatbot through WhatsApp. They can ask questions regarding their (or the patient they are caring for) prescribed medications and get immediate responses from the chatbot. The intervention will last for 7 days.

Other: An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia

Control group

NO INTERVENTION

The control group will not have any exposure with the chatbot during the intervention period.

Interventions

It is a chatbot for HA-prescribed medication used for treating hyperglycaemia, hypertension, and hyperlipidaemia, available through WhatsApp. All the responses will be extracted from a database, in which the content was obtained from and validated by pharmacists from the Chief Pharmacist's Office of the Hospital Authority in Hong Kong. The intervention period will last for 7 days.

Pharmacy chatbot intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients aged 18 years or older diagnosed with either hyperglycaemia, hypertension, or hyperlipidaemia, and currently receiving medication prescribed by the Hospital Authority in Hong Kong.
  • Caregivers aged 18 years or older for patients described above.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Laboratory of Data Discovery for Health

Hong Kong, Hong Kong

RECRUITING

The University of Hong Kong

Hong Kong, Hong Kong

RECRUITING

MeSH Terms

Conditions

HyperglycemiaHypertensionHyperlipidemias

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesVascular DiseasesCardiovascular DiseasesDyslipidemiasLipid Metabolism Disorders

Study Officials

  • Joseph Wu, PhD

    The University of Hong Kong

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Joseph Wu, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 17, 2025

First Posted

June 25, 2025

Study Start

June 1, 2025

Primary Completion (Estimated)

October 31, 2026

Study Completion (Estimated)

October 31, 2026

Last Updated

June 25, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will share

Individual participant data that underlie the results reported in the article, after de-identification (text, tables, figures, and appendices), will be shared. A written data-sharing request for meta-analysis should be submitted by email with a methodologically sound proposal. To gain access, data requestors will need to sign a data access agreement.

Shared Documents
STUDY PROTOCOL
Time Frame
Beginning 9 months and ending 36 months following article publication
Access Criteria
Researchers who provide a methodologically sound proposal for meta-analysis. To gain access, data requestors will need to sign a data access agreement.

Locations