Impact of Preoperative Sleep Quality and Anxiety on Postoperative Outcomes in Abdominal Gynecologic Cancer Surgery

NCT07036549 | Completed

• 1 other identifier: ISHSLANXPAIN
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective observational study aims to evaluate the effects of preoperative sleep quality and anxiety levels on postoperative outcomes in patients undergoing abdominal gynecologic cancer surgery. A total of 72 patients were included and assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Beck Anxiety Inventory (BAI) prior to surgery. Postoperative outcomes including pain scores (measured by the Numeric Rating Scale), complication rates, additional analgesic use, and length of hospital stay were recorded. The findings suggest that poor sleep quality and high anxiety levels prior to surgery are significantly associated with higher postoperative pain, increased complication rates, and prolonged hospital stay. These results emphasize the importance of preoperative psychological evaluation and supportive interventions to improve perioperative care in gynecologic oncology.

Conditions

Gynecologic Neoplasms

Keywords

Sleep Quality; Anxiety; Postoperative Pain; Gynecologic Cancer Surgery; Preoperative Assessment; Patient Outcomes; Psychological Stress; Hospital Stay

Outcome Measures

Primary Outcomes (1)

• Postoperative Pain Score (Numeric Rating Scale)

  Postoperative pain will be assessed using the Numeric Rating Scale (NRS) at 0, 4, 8, 12, and 24 hours after surgery. Higher scores indicate greater pain intensity.

  Postoperative Day 1 (within 24 hours after surgery)

Secondary Outcomes (3)

• Postoperative Complication Rate

  Up to 30 days after surgery

• Additional Analgesic Requirement

  Postoperative Day 1 (within 24 hours after surgery)

• Length of Hospital Stay

  From day of surgery until discharge (mean: 4.2 days)

Study Arms (1)

Surgical Cohort

Patients undergoing abdominal gynecologic cancer surgery were prospectively observed for postoperative outcomes including pain, complications, analgesic requirement, and hospital stay. Preoperative sleep quality and anxiety levels were measured and analyzed in relation to clinical outcomes.

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: Only biologically female individuals undergoing gynecologic cancer surgery were eligible to participate.
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Female patients aged 18 years or older undergoing abdominal surgery for gynecologic malignancies at a tertiary oncology center between February and May 2025.

You may qualify if:

• Female patients aged ≥18 years
• Diagnosed with gynecologic malignancy
• Scheduled for elective abdominal surgery (laparotomy)
• Able to provide informed consent
• Completed preoperative sleep and anxiety assessments

You may not qualify if:

• History of psychiatric or cognitive disorders interfering with questionnaire participation
• Emergency surgical procedures
• Incomplete follow-up data within 30 days postoperatively
• Patients admitted for inpatient observation prior to surgery
• Major previous pelvic surgery

Sponsors & Collaborators

• Izmir City Hospital: lead

Study Sites (1)

İzmir City Hospital

Izmir, Turkey (Türkiye)

Location

Related Publications (1)

• Akdemir C, Turan SA, Balci MF, Ozen S, Seker N, Bayramoglu D, Bayramoglu Z, Sanci M. Preoperative sleep quality and anxiety as predictors of postoperative pain and recovery in Gynecologic oncology surgery: A prospective observational study. J Psychosom Res. 2026 Feb;201:112496. doi: 10.1016/j.jpsychores.2025.112496. Epub 2025 Dec 11.

  PMID: 41389754 DERIVED

MeSH Terms

Conditions

Genital Neoplasms, Female; Sleep Initiation and Maintenance Disorders; Anxiety Disorders; Pain, Postoperative; Stress, Psychological

Condition Hierarchy (Ancestors)

Urogenital Neoplasms; Neoplasms by Site; Neoplasms; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Mental Disorders; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms; Behavioral Symptoms; Behavior

Study Officials

• Celal Akdemir, md

  Izmir City Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD

Study Record Dates

• First Submitted: June 17, 2025
• First Posted: June 25, 2025
• Study Start: February 15, 2025
• Primary Completion: March 20, 2025
• Study Completion: May 15, 2025
• Last Updated: June 25, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)