Sleep, Mood, and Quality of Life Issues in ASD Adolescents and Adults.

NCT07033078 | Active Not Recruiting

• 1 other identifier: 202400427B0
• Study Type: observational
• Target: 166
• Locations: 1 country
• Sites: 1

Brief Summary

Autism Spectrum Disorder (ASD) presents unique challenges, particularly in sleep, mood, and quality of life for adolescents and adults. Due to the pressures of life they face, these groups may experience more severe sleep problems and emotional issue and associated issues than children. Current research on these sleep and emotional issues in older ASD individuals is limited, and there is a need for studies on various sleep and emotional problems they encounter. This study aims to compare sleep patterns in adolescents and adults with Asperger's syndrome and high-functioning autism using both subjective and objective measures, such as questionnaires and polysomnography. It also examines the factors influencing sleep, including cognitive function, emotional and behavioral problems, and quality of life. Additionally, the study evaluates the reliability and validity of the Chinese Social Responsiveness Scale-Adult Version in Taiwan. The expected outcome is that sleep and emotional issues in these populations are linked to anxiety, depression, poorer functioning, and lower quality of life.

Conditions

Autism Spectrum Disorder

Keywords

Asperger Disorder; High Functioning Autism; Sleep; Polysomnography; Actigraphy

Outcome Measures

Primary Outcomes (1)

• Actigraphy

  Using actigraphy to assess the differences in sleep patterns between individuals with Autism Spectrum Disorder (ASD) and typically developing controls.

  7 days

Study Arms (2)

ASD

Asperger

Eligibility Criteria

• Age: 13 Years - 45 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by core symptoms such as social communication difficulties and repetitive behaviors.

You may qualify if:

• Subjects diagnosed by a psychiatrist as meeting the DSM-IV-TR diagnosis of Asperger's syndrome or autism.
• Subjects were aged between 13-45 years old, male or female.
• The subjects and their families agree to join the trial and sign the subject consent form.

You may not qualify if:

• Cases where clinical assessment cannot be combined with sleep examination.
• Cases where the intelligence test result showed that the full scale IQ was \<70.
• Those with serious physiological diseases, such as congenital heart disease, thyroid dysfunction, immune deficiency diseases, severe autoimmune diseases, brain injuries or severe organic brain diseases, which will affect the evaluation results.
• Severe mental illness, such as severe schizophrenia, bipolar disorder, etc.
• Not willing to participate in this study or unwilling to fill out the consent form.
• Those who are not suitable to enter the trial after being evaluated by the PI and co-PI.

Sponsors & Collaborators

• Chang Gung Memorial Hospital: lead

Study Sites (1)

Chang Gung Memorial Hospital

Taoyuan District, Taiwan, 333, Taiwan

Location

MeSH Terms

Conditions

Autism Spectrum Disorder; Asperger Syndrome

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 13, 2025
• First Posted: June 24, 2025
• Study Start: July 1, 2024
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: June 24, 2025

Record last verified: 2024-07

Locations

TW (1)