Diagnosis of Wire Syndrome

NCT07030023 | Enrolling By Invitation

• 1 other identifier: 25Ondonto03
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The Wire Syndrome (WS) refers to aberrant, unexpected, unexplained, or excessive dental movements involving teeth held by an intact post-orthodontic retention wire. Its prevalence ranging from 1.1% to 43%. It is a chronic, progressive pathological process, generally asymptomatic, resulting in a new malocclusion that is not due to relapse or a physiological process, and whose aesthetic and/or functional dento-periodontal consequences are harmful. The causes are multifactorial origin. In the early stages of Wire Syndrome, dental and periodontal consequences are minors. These issues are thought to progressively worsen over time.However, to date, no author has proposed an appropriate diagnostic approach. Indeed, several diagnostic criteria have been reported in the literature, but their hierarchical ranking, in terms of importance and specificity, has yet to be determined. The main objective of this study is therefore to propose a classification of WS according to its severity, based on a shared framework between periodontists and orthodontists. This classification should, facilitate early detection of the syndrome, and reduce diagnostic delays and therapeutic errors. It should also help clarify prognosis and improve interprofessional collaboration in developing personalized treatment plans.

Conditions

Orthodontic Wires

Outcome Measures

Primary Outcomes (2)

• Presence of Wire Syndrome

  The presence of Wire Syndrome was clinically evaluated (based on photographs) under 2 answers "Yes" or "No".

  At the inclusion

• severity classification of Wire Syndrome

  Severity was categorized into three grades such as minor, moderate, and severe based on dental and periodontal parameters.

  At the inclusion

Secondary Outcomes (2)

• Major clinical diagnosis criteria (Fleiss Kappa)

  At the inclusion

• Minor clinical diagnostis criteria (Fleiss Kappa)

  At the inclusion

Study Arms (1)

Wire syndrome patients

Other: Non intervention

Interventions

Non intervention OTHER

Non intervention

Wire syndrome patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population consists of patients who have undergone orthodontic treatment and are currently wearing a fixed orthodontic retainer

You may qualify if:

• Presence of fixed orthodontic retention (maxillary and/or mandible)
• Comprehensive documentation available
• Systemically healthy
• Presence or not of a Wire Syndrome

You may not qualify if:

• Patient with other orthodontic retention.
• Patient unable to understand french

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nice: lead

Study Sites (1)

CHU NICE

Nice, Alpes Maritimes, 06 000, France

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 12, 2025
• First Posted: June 19, 2025
• Study Start: March 28, 2025
• Primary Completion: July 31, 2025
• Study Completion: July 31, 2025
• Last Updated: June 19, 2025

Record last verified: 2025-05

Locations

FR (1)