Study Stopped
The study was halted due to time constraints
Neural Mobilization Exercises on Pain and Central Sensitization
The Effect of Neural Mobilization Exercises on Pain and Central Sensitization in Individuals With Lateral Epicondylitis: A Randomized Controlled Trial
1 other identifier
interventional
30
1 country
1
Brief Summary
This study aims to investigate the effects of neural mobilization exercises on central sensitization and pain characteristics in individuals with lateral epicondylitis. Enrolled participants will be randomly assigned to two groups. One group will receive routine exercises and ESWT treatment, while the other group will receive neural mobilization exercises in addition to routine exercises and ESWT treatment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 2, 2025
CompletedFirst Posted
Study publicly available on registry
June 18, 2025
CompletedStudy Start
First participant enrolled
February 1, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 1, 2027
February 23, 2026
February 1, 2026
1 year
June 2, 2025
February 19, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Central Sensitization
pressure pain threshold
baseline and after the 8 sessions (4th week)
Secondary Outcomes (2)
Central Sensitization
baseline and after the 8 sessions (4th week)
Pain Catastrophizing
baseline and after the 8 sessions (4th week)
Study Arms (2)
mobilization
EXPERIMENTALparticipants will receive additional median nerve mobilizations
control
ACTIVE COMPARATORparticipants will receive routine exercises
Interventions
eccentric strengthening exercises
An exercise to increase median nerve mobility by flexing and extending fingers, wrist, elbow, shoulder, and neck
Eligibility Criteria
You may qualify if:
- Clinical diagnosis of lateral epicondylitis
- years old
You may not qualify if:
- Any other pathology, disease, condition, pain, surgery on the elbow, wrist, fingers, shoulder, or neck in the last year
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Izmir Katip Celebi University
Izmir, Turkey (Türkiye)
Related Publications (1)
Coombes BK, Bisset L, Vicenzino B. Management of Lateral Elbow Tendinopathy: One Size Does Not Fit All. J Orthop Sports Phys Ther. 2015 Nov;45(11):938-49. doi: 10.2519/jospt.2015.5841. Epub 2015 Sep 17.
PMID: 26381484BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
kevser sevik kacmaz, pt, phd
Izmir Katip Celebi University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- research asisstant, phd
Study Record Dates
First Submitted
June 2, 2025
First Posted
June 18, 2025
Study Start
February 1, 2026
Primary Completion (Estimated)
February 1, 2027
Study Completion (Estimated)
March 1, 2027
Last Updated
February 23, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will not share