Effects of Buteyko Breathing Exercise in Children With Uncontrolled Asthma

NCT07025616 | Not Yet Recruiting

• 1 other identifier: 24-07-1177
• Study Type: interventional
• Target: 74
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with uncontrolled asthma.

Conditions

Breathing Techniques; Asthma Control Level; Asthma in Children; Asthma Patients; Breathing Exercise

Keywords

Asthma; Buteyko; breathing retraining; pediatrics

Outcome Measures

Primary Outcomes (1)

• Asthma control

  Level of asthma control measured by Asthma Control Questionnaire (ACQ) - Indonesian version. Minimum value 0, maximum value 6. Higher score means worse outcome.

  At enrollment and end of fourth-week

Secondary Outcomes (7)

• Asthma Quality of Life

  At enrollment and end of fourth-week

• Bronchodilator use

  At end of fourth-week

• FEV1

  At enrollment and end of fourth-week

• FVC

  At enrollment and end of fourth-week

• FEV1/FVC

  At enrollment and end of fourth-week

Study Arms (2)

Buteyko

EXPERIMENTAL

Buteyko breathing exercise plus pharmacological treatment

Behavioral: Buteyko; Drug: Asthma reliever and controller

Control

ACTIVE COMPARATOR

Pharmacological treatment

Drug: Asthma reliever and controller

Interventions

Buteyko BEHAVIORAL

The Buteyko breathing exercise is a method that encourages nasal breathing, reducing breathing volume, and using breath-holding exercises to normalize breathing pattern

Buteyko

Asthma reliever and controller DRUG

Asthma reliever and controller according to GINA (Global Initiative for Asthma) guideline

Buteyko; Control

Eligibility Criteria

• Age: 7 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children aged 7-17 years
• Uncontrolled or partially controlled asthma (GINA Symptom Control Tool score \> 1)
• Receive bronchodilator therapy, either oral or inhaler from a pediatrician.
• Children and parents/care givers agree to participate in the study until the end, and parents/care givers sign the informed consent form.
• Can understand instructions.

You may not qualify if:

• Inpatients
• Have received Buteyko breathing exercises or other breathing exercises.
• Have congenital heart disease, pneumonia, or other significant and uncontrolled health disorders.
• Have severe physical disabilities or mental retardation that could potentially prevent the implementation of Buteyko breathing exercises.
• Have contraindications for spirometry examination

Sponsors & Collaborators

• Ivan Sofian Wibowo: lead
• Fakultas Kedokteran Universitas Indonesia: collaborator
• Dr Cipto Mangunkusumo General Hospital: collaborator

Study Sites (1)

Universitas Indonesia, Faculty of Medicine

Jakarta Pusat, Dki Jakarta, 10430, Indonesia

Location

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Central Study Contacts

Ivan S Wibowo, Medical Doctor

CONTACT

+6285647581213; ivan_sofian@yahoo.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: dr.

Study Record Dates

• First Submitted: June 8, 2025
• First Posted: June 17, 2025
• Study Start: June 1, 2025
• Primary Completion: December 1, 2025
• Study Completion: December 1, 2025
• Last Updated: June 17, 2025

Record last verified: 2025-06

Locations

ID (1)