NCT07022639

Brief Summary

The effect of centralisation measures on the operative outcomes after pancreatic resection in Switzerland has not been highlighted yet. This study aims to investigate the influence of the annual hospital specific case load of pancreatic resection on short-term postoperative outcomes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6,785

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2013

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2013

Completed
10 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2023

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

May 26, 2025

Completed
20 days until next milestone

First Posted

Study publicly available on registry

June 15, 2025

Completed
Last Updated

July 10, 2025

Status Verified

July 1, 2025

Enrollment Period

10 years

First QC Date

May 26, 2025

Last Update Submit

July 9, 2025

Conditions

Pancreatic Diseases

Outcome Measures

Primary Outcomes (1)

  • Mortality

    The association between the hospital volume and the postoperative mortality Mortality Yes or No Hospital volume of pancreatic resection as marginal effect Association with GAM logistic regression

    Periprocedural

Secondary Outcomes (3)

  • Reoperation

    Periprocedural

  • Length of hospital stay

    Periprocedural

  • Sociodemographic trends

    2013 - 2022

Study Arms (3)

Total pancreatectomy

Procedure: Total pancreatectomy

Proximal pancreatectomy

Procedure: Proximal pancreatectomy

Distal pancreatectomy

Procedure: Distal pancreatectomy

Interventions

Total pancreatectomyPROCEDURE

Total pancreatectomy for any kind of disease

Total pancreatectomy
Proximal pancreatectomyPROCEDURE

Proximal pancreatectomy for any kind of disease

Proximal pancreatectomy
Distal pancreatectomyPROCEDURE

Distal pancreatectomy for any kind of disease

Distal pancreatectomy

Eligibility Criteria

Age20 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients with pancreatic resection in Switzerland between 2013 and 2022.

You may qualify if:

  • All patients with pancreatic resection in Switzerland between 2013 and 2022

You may not qualify if:

  • incomplete case documentation
  • age under 20 years
  • other hospitals than general or surgical hospitals
  • no index operation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HOCH Health Ostschweiz, Kantonsspital St.Gallen

Sankt Gallen, St.Gallen, 9000, Switzerland

Location

MeSH Terms

Conditions

Pancreatic Diseases

Condition Hierarchy (Ancestors)

Digestive System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
90 Days
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 26, 2025

First Posted

June 15, 2025

Study Start

January 1, 2013

Primary Completion

December 31, 2022

Study Completion

March 1, 2023

Last Updated

July 10, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Locations

CH(1)