NCT07020962

Brief Summary

The aim of this study is to examine the effect of laughter therapy applied to breast cancer patients before surgical intervention on distress, depression and psychological well-being of patients. This research will be carried out as an experimental research with a randomised control group. The population of the study will consist of breast cancer patients diagnosed with breast cancer in a city hospital and scheduled for surgery in the breast-endocrine surgery clinic. The research will be carried out with patients who meet the inclusion criteria and agree to participate in the study. The sample size for the study was calculated using the G\* Power 3.1.9.7 programme (Faul et al., 2007). In the calculation, since there was no similar study for two-way mixed design analysis of variance, the required sample size was calculated as 48, 24 in each group, based on the medium effect size (effect size f=0.25), 5% margin of error (alpha=0.05), inter-measurement correlation value 0.5 and 80% power (1-β=0.80). Considering the data losses, the number was increased by 20% and a total of 56 patients in the intervention and control groups constituted the sample of the study. Hypothesis(es): H1: The effect of laughter therapy applied to breast cancer patients on distress over time is different in the experimental and control groups. H2: The effect of laughter therapy applied to breast cancer patients on depression over time is different in the experimental and control groups. H3: The effect of laughter therapy applied to breast cancer patients on psychological well-being according to time is different in experimental and control groups. In obtaining the research data; Personal Information Form, Distress Thermometer, Psychological well-being scale prepared by the researchers in line with the literature will be used. The research data will be collected face-to-face through data collection forms from breast cancer patients diagnosed with breast cancer and scheduled for surgery in the breast-endocrine surgery clinic. Individuals who agree to participate in the study and meet the inclusion criteria will be assigned to the experimental and control groups by providing randomisation. Which caregivers will be in the intervention group and which will be in the control group will be determined according to the randomisation table determined by https://www.randomizer.org/ over the internet. Group 1: Intervention Group, Group 2: Control Group. Data collection tools will be applied to the individuals in the experimental and control groups as a pre-test. Individuals in the experimental group will receive laughter therapy three days a week for 30-45 minutes (6 sessions). Individuals in the control group will receive only standard nursing care. Data collection tools will be applied to the individuals in both groups for post-test, 1 and 3-month follow-up tests immediately after all laughter sessions with the experimental group are completed.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 25, 2025

Completed
2 months until next milestone

First Posted

Study publicly available on registry

June 13, 2025

Completed
12 days until next milestone

Study Start

First participant enrolled

June 25, 2025

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2025

Completed
Last Updated

June 13, 2025

Status Verified

June 1, 2025

Enrollment Period

2 months

First QC Date

April 25, 2025

Last Update Submit

June 12, 2025

Conditions

Keywords

breast cancerpsychological well-beingdepressiondistresslaughter therapy

Outcome Measures

Primary Outcomes (3)

  • Laughter therapy will be applied to individuals with breast cancer and their levels of psychological distress will be measured.Laughter therapy will be applied to individuals with breast cancer and their psychological distress levels will be measured.

    Meme kanserine sahip olan bireylere kahkaha terapisi uygulanacak ve pskilojik sıkıntı düzeyleri ölçülecektir. Laughter therapy will be applied to individuals with breast cancer and their levels of psychological distress will be measured. (Face to face training will be given)

    2 weeks

  • Laughter therapy will be applied to individuals with breast cancer and their depression levels will be measured.

    Laughter therapy will be applied to individuals with breast cancer and their depression levels will be measured (Face to face training will be given)

    2 weeks

  • Laughter therapy will be applied to individuals with breast cancer and their psychological well-being levels will be measured.

    Laughter therapy will be applied to individuals with breast cancer and their psychological well-being levels will be measured (Face to face training will be given)

    2 weeks

Study Arms (2)

Experimental group

EXPERIMENTAL

Laughter therapy

Other: laughter therapy

control group

ACTIVE COMPARATOR

routine nursing care

Other: routine nursing care

Interventions

Laughter therapy/yoga, classified as complementary therapy in medicine, is a unique form of exercise consisting of a combination of laughter, yoga and breathing techniques that allows us to laugh without any sense of humour.

Experimental group

routine nursing care

control group

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Voluntary acceptance to participate in the study,
  • Being diagnosed with breast cancer and being in the patient group in which surgical operation is planned,
  • Not having participated in laughter yoga practice before,
  • Being literate,
  • Not having a psychiatric disease (diagnosis)
  • Not having a communication and understanding disability related to vision, hearing
  • Being in the age group of 18 and over

You may not qualify if:

  • Not wanting to participate in the study,
  • Being in the patient group with a condition recommended not to do laughter yoga (having undergone surgery in the abdominal region in the last three months, uncontrolled hypertension, glaucoma, hernia, epilepsy),
  • Not having participated in any of the laughter yoga sessions,
  • Having physical restriction/respiratory problems and not being able to perform yoga movements.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Psychological Well-BeingBreast NeoplasmsDepression

Interventions

Laughter Therapy

Condition Hierarchy (Ancestors)

Personal SatisfactionBehaviorNeoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue DiseasesBehavioral Symptoms

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeutics

Study Officials

  • Servet Cihan

    Prof. Dr. Cemil Taşcıoğlu Şehir Hastanesi

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Tuğba Pehlivan Sarıbudak

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
CARE PROVIDER
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Education nurse

Study Record Dates

First Submitted

April 25, 2025

First Posted

June 13, 2025

Study Start

June 25, 2025

Primary Completion

August 30, 2025

Study Completion

October 30, 2025

Last Updated

June 13, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share