Correlation of Dry Eye Disease, Problematic Smartphone Use and Sleep Quality in Adolescents and Young Adults

NCT07020871 | Not Yet Recruiting DMC

• 1 other identifier: 2024KYPJ090
• Study Type: observational
• Target: 453
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to learn about the status quo and relationship of dry eye, problematic smartphone use, bedtime procrastination, and sleep in adolescents and young adults. The main questions it aims to answer are:

• Is there a positive correlation between problematic smartphone use and dry eye?
• Is problematic smartphone use positively correlated with bedtime procrastination?
• Is bedtime procrastination negatively correlated with sleep quality?
• Is there a negative correlation between sleep quality and dry eye?
• Is there a negative correlation between problematic smartphone use and sleep quality?
• Is there a positive correlation between bedtime procrastination and dry eye?
• Do bedtime procrastination and sleep quality serve as mediating factors in the relationship of problematic smartphone use and dry eye? Participants will be asked to complete several questionnaires and dry eye related examinations.

Conditions

Dry Eye Disease (DED)

Keywords

dry eye disease; problematic smartphone use; sleep quality; bedtime procrastination; adolescents and young adults

Outcome Measures

Primary Outcomes (4)

• Dry eye symptoms

  Ocular Surface Disease Index scale with 12-item will be used to measure dry eye symptoms. The scale uses Likert 5 comments, with a total score ranging from 0 to 100. And the total score reaching or exceeding 13 points indicates that participants exhibit symptoms of dry eye.

  baseline

• Problematic smartphone use

  The 10-item Smartphone Addiction Scale Short Version will be used to measure the problematic smartphone use. The scale uses Likert 6 comments, with a total score ranging from 10 to 60. And higher scores indicate more severe problematic smartphone use.

  baseline

• sleep quality

  The Pittsburgh Sleep Quality Index scale is used to measure participants' sleep quality. The total score ranges from 0 to 21. Higher scores indicate lower quality of sleep.

  baseline

• bedtime procrastination

  There are 9 items in the Bedtime Procrastination Scale, which is used to measure participants' bedtime procrastination. The scale uses 5-point scale, with a total score ranging from 9 to 45. And higher scores indicate more severe procrastination before sleep.

  baseline

Secondary Outcomes (2)

• Perceived level of stress

  baseline

• non-invasive tear film break-up time

  baseline

Other Outcomes (3)

• Tear meniscus height

  baseline

• Meibomian gland loss

  baseline

• Lipid layer thickness (LLT) and blinking pattern

  baseline

Study Arms (1)

Investigation Team

1. After informed consent, adolescents and young adults aged 14-35 years old (including 14,35 years old) are assessed by questionnaires and dry eye related examinations. 2. The main content is Investigating the relationship among dry eye disease, problematic smartphone use, bedtime procrastination, and sleep quality.

Eligibility Criteria

• Age: 14 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

General adolescents and young adults between 14-35 years old

You may qualify if:

• Adolescents and young adults aged 14 to 35 (including 14,25 years old) ;
• Agree to participate in the studies

You may not qualify if:

• Unable to communicate normally;
• With ocular surface diseases other than dry eye and autoimmune diseases;
• Use drugs that may cause damage to the ocular surface, such as anti glaucoma drugs, antidepressants, sex hormones, chemotherapy drugs, etc.;
• With a history of eye trauma or eye surgery;
• With a history of wearing contact lenses within the past month;
• Pregnant and lactating women

Sponsors & Collaborators

• Wei XIA, PhD: lead

Study Sites (1)

Sun Yat-sen University

Guangzhou, Guangdong, 510080, China

Location

MeSH Terms

Conditions

Dry Eye Syndromes; Sleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

Lacrimal Apparatus Diseases; Eye Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Mental Disorders

Study Officials

• Wei Xia PhD

  Sun Yat-sen University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Wei Xia PhD

CONTACT

+8618823359471; xiaw23@mail.sysu.edu.cn

Shuping Li Master

CONTACT

+8618826073426; lishpy@163.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: June 5, 2025
• First Posted: June 13, 2025
• Study Start: July 20, 2025
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: July 10, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)