NCT07020364

Brief Summary

A prospective feasibility study would be a practical first step, focusing on real-time assessment and ensuring the new working element's integration is safe and effective before broader clinical trials.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2024

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2024

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 26, 2024

Completed
7 months until next milestone

First Posted

Study publicly available on registry

June 13, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2025

Completed
Last Updated

June 13, 2025

Status Verified

June 1, 2025

Enrollment Period

12 months

First QC Date

November 26, 2024

Last Update Submit

June 4, 2025

Conditions

Keywords

laser enucleationbipolar enucleationBPHprostate

Outcome Measures

Primary Outcomes (2)

  • Feasibility

    Successful completion of enucleation using the single working element. Time taken to switch between bipolar and laser modalities.

    the operative time

  • Safety

    intraoperative complications (bleeding, urethral damage). Postoperative complications (infections, catheterization time, hospital stay).

    1 month

Secondary Outcomes (2)

  • Efficacy

    1 month

  • Cost Analysis

    the operative time

Study Arms (2)

Bipolar Enucleation

Bipolar Enucleation Group: The bipolar energy will be used for cutting and coagulation during enucleation.

Device: A single working element for bipolar enucleation

Laser Enucleation

Laser Enucleation Group: Thulium or Holmium laser will be employed for tissue dissection and hemostasis.

Device: A single working element for laser enucleation

Interventions

Device: A single working element compatible with both bipolar and laser modalities. The bipolar energy will be used for cutting and coagulation during enucleation.

Bipolar Enucleation

Device: A single working element compatible with both bipolar and laser modalities. Thulium or Holmium laser will be employed for tissue dissection and hemostasis.

Laser Enucleation

Eligibility Criteria

Age50 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

the study will include male patients aged ≥50 years who are diagnosed with benign prostatic hyperplasia (BPH) , prostate volume ≥40 cc without 4prior history of prostate cancer while patients with ongoing urinary tract infections, prior prostate surgeries, coagulopathy or urethral strictures were excluded.

You may qualify if:

  • Diagnosed with benign prostatic hyperplasia (BPH) requiring surgical intervention.
  • Prostate volume ≥40 cc (as assessed by transrectal ultrasound).
  • No prior history of prostate cancer.

You may not qualify if:

  • Patients with ongoing urinary tract infections.
  • Prior prostate surgeries.
  • Coagulation disorders or patients on long-term anticoagulation therapy.
  • Known urethral strictures or other anatomical abnormalities complicating endoscopic procedures.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Menoufia Faculty of Medicine

Shibīn al Kawm, Menoufia, 13829, Egypt

RECRUITING

MeSH Terms

Conditions

Prostatic Hyperplasia

Condition Hierarchy (Ancestors)

Prostatic DiseasesGenital Diseases, MaleGenital DiseasesUrogenital DiseasesMale Urogenital Diseases

Central Study Contacts

Mohamed K Omar, Assistant professor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

November 26, 2024

First Posted

June 13, 2025

Study Start

October 1, 2024

Primary Completion

September 30, 2025

Study Completion

November 1, 2025

Last Updated

June 13, 2025

Record last verified: 2025-06

Locations