Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD

NCT07020182 | Not Yet Recruiting DMC

• 1 other identifier: INPATIENT COPD REHABILITATION
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The study aimed to identify the effect of early pulmonary rehabilitation in elderly patients with Acute exacerbation (AE) of COPD (AECOPD) in exercise tolerance, dyspnea, sleep quality, fatigue, and time to discharge from hospital.

Conditions

COPD Received PR; Elderly (People Aged 65 or More); COPD; COPD Acute Exacerbation

Keywords

Elderly patients with acute exacerbation of COPD

Outcome Measures

Primary Outcomes (1)

• Exercise tolerance

  The 6 minute walk test(6MWT)in meter to asses exercise tolerance

  The study will be start from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

Secondary Outcomes (3)

• Dyspnea

  The study will be start from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

• Length of hospital stay(LOS)

  The study will be start from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

• Fatigue level

  The study will be start from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

Study Arms (2)

Group A will perform physical therapy program

EXPERIMENTAL

Study group In this study we will study the impact of exercise training include breathing exercise, low-load resistance exercise (15%-30% of 1 repetition maximum (1-RM) as tolerated), aerobic training in the form of walking exercise under supervision of physiotherapist.In patients exercise tolerance, dyspnea, fatigue, and time to discharge from hospital. The study will be start from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

Other: physical therapy program

Group B will the control group

NO INTERVENTION

control group

Interventions

physical therapy program OTHER

Group A will performed a physical therapy program that completed two daily sessions till discharge from the hospital .Exercise training starts from randomisation until hospital discharge,and administered twice per day, seven times per week. The study will be start from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

Group A will perform physical therapy program

Eligibility Criteria

• Age: 65 Years - 78 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Patients with acute exacerbation of COPD in both gender
• Patient older than 65 years
• Patient with clear consciousness
• Patients had been diagnosed with shortness of breath or dyspnea that was not caused by heart disease, pneumothorax, or pulmonary edema

You may not qualify if:

• Patient with systolic blood pressure lower than 90 mmHg
• Patient with an unstable psychological status, hemoptysis, pneumothorax, pulmonary edema

Sponsors & Collaborators

• Al-Azhar University: lead

Study Sites (1)

Faculty of Medicine for Girls- Al-Azhar-University, Cairo, Egypt

Cairo, 02, Egypt

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Mohammed, phd

  Al-Azhar University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Marwa Mohammed, Phd -university lecturer

CONTACT

+201000253865; dr.marwamohammed@p.bsu.edu.eg

Marwa Mohammed

CONTACT

dr.marwamohammed@p.bsu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: The codes were determined by using serially numbered block size will be kept in sealed and opaque envelopes in a locked office
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of physical therapy,Beni-suef University

Model Details: A prospective supervised RCT (Randomized Controlled Trial) will be done include elderly COPD patients assigned randomly into two groups; Group A performed physical therapy program, and Group B is control group completed two daily sessions from day 1 of hospital admission till discharge from the hospital.The study duration will be 12 weeks

Study Record Dates

• First Submitted: May 10, 2025
• First Posted: June 13, 2025
• Study Start: June 10, 2025
• Primary Completion: September 10, 2025
• Study Completion: September 15, 2025
• Last Updated: June 13, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)