Assessing the Effect of Different Grades of Chondromalacia on Static and Dynamic Balance Using Biodex Balance System

NCT07014787 | Recruiting DMC

• 1 other identifier: P.T.REC/012/005573
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the effect of grades of chondromalacia on static and dynamic balance.

Conditions

Chondromalacia Patella

Keywords

Biodex balance system static and dynamic balance assessment of chondromalacia

Outcome Measures

Primary Outcomes (1)

• Measuring static and dynamic balance

  Measuring static and dynamic balance using biodex balance system

  up to four weeks

Study Arms (5)

Control Group

Control group of 20 healthy patients Normal MRI Study

grade I chondromalacia.

Experimental group of 20 patients with grade I chondromalacia Softening and swelling, intact surface Nearly normal (soft indentation and/or superficial fissures and cracks) Increased T2 signal intensity of morphologically normal cartilage

grade II chondromalacia

Experimental group of 20 patients with grade II chondromalacia. Fragmentation and fissuring of articular cartilage affecting an area of less than 0.5 inches Abnormal (lesions extending to \<50% of cartilage depth) A: Superficial partial-thickness cartilage defect \<50% of total articular surface thickness B: Deep partial-thickness cartilage defect \>50% of total articular surface thickness

grade III chondromalacia

Experimental group of 20 patients with grade III chondromalacia Fragmentation and fissuring of articular cartilage affecting an area greater than 0.5 inches Severely abnormal (lesions extending \>50% of cartilage depth, but not through subchondral bone) Full-thickness cartilage defect

grade IV chondromalacia

Experimental group of 20 patients with grade IV chondromalacia Cartilage erosion to bone Lesions involving subchondral bone

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

100 patients, 80 with different grades of chondromalacia (Grade I, II, III, IV) with 20 participants in each group and 20 healthy participants in the control group will be recruited for the study.

You may qualify if:

• Age ranged from 18 to 40 years old
• groups include both males and females
• Patients with Grade I, II, III and IV chondromalacia: Confirmation of diagnosis by MRI
• BMI will be ranged from 19.0 to 29.0
• Patients with Unilateral or bilateral chondromalacia.
• Chronic cases for more than 3 months.
• Positive sign of Knee pain according to patellar Grind Test

You may not qualify if:

• patients have not undergone knee replacement.
• patients have not done Intra-articular injection in the affected knee for the past 3 months.
• Patients with rheumatoid arthritis or other inflammatory arthritis.
• Patients with Vestibular disorders or neurological conditions.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of physical therapy Cairo University

Giza, 12518, Egypt

RECRUITING

MeSH Terms

Conditions

Chondromalacia Patellae

Condition Hierarchy (Ancestors)

Cartilage Diseases; Musculoskeletal Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases

Study Officials

• Selwan Khaled Ayad, Teacher Assistant

  Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Selwan Khaled Ayad, teacher Assistant

CONTACT

+201064709563; selwan_kayad@outlook.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Teaching Assistant

Study Record Dates

• First Submitted: June 3, 2025
• First Posted: June 11, 2025
• Study Start: November 5, 2024
• Primary Completion: May 30, 2025
• Study Completion: June 15, 2025
• Last Updated: June 11, 2025

Record last verified: 2025-06

Locations

EG (1)