Correlation Between Motor Control Dysfunction and Radiographic Parameter in Non Specific Chronic Low Back Pain

NCT07013786 | Not Yet Recruiting

• 1 other identifier: CUFPT-TRIAL001
• Study Type: observational
• Target: 64
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to investigate the relationship between motor control dysfunction (MCD) and radiographic parameters in non-specific chronic low back pain (NSCLBP). Participants will undergo specific clinical motor control tests and lumbar spine X-rays to evaluate the alignment and coordination of spinal and pelvic structures. Understanding this relationship may help improve rehabilitation strategies and reduce pain in affected individuals.

Conditions

Chronic Non Specific Low Back Pain

Keywords

Lumbar motor control dysfunction; Lumbopelvic parameters; Radiographic alignment; Transverse abdominis; Multifidus

Outcome Measures

Primary Outcomes (5)

• Lumbar Lordotic Angle

  Radiographic measurement of the lumbar lordotic angle (LLA) in degrees to assess sagittal spinal alignment in patients diagnosed with non-specific chronic low back pain.

  At baseline (during initial assessment visit)

• Pelvic Incidence Angle

  Measurement of Pelvic Incidence Angle in degrees obtained from lateral radiographic imaging in patients with non-specific chronic low back pain.

  At baseline (during initial assessment visit)

• Pelvic Tilt Angle

  Assessment of pelvic tilt angle in degrees as part of the evaluation of lumbopelvic alignment in patients with non-specific chronic low back pain.

  At baseline (during initial assessment visit)

• Sacral Slope Angle

  Evaluation of sacral slope angle in degrees based on standard radiographic imaging in patients with non-specific chronic low back pain.

  At baseline (during initial assessment visit)

• Lumbar Motor Control Assessment via Pressure Biofeedback during ADIM

  Evaluation of lumbar motor control using pressure biofeedback during the Abdominal Draw-In Maneuver (ADIM) from crook lying and prone position. Pressure changes in mmHg will be recorded to assess the ability to maintain abdominal contraction.

  At baseline (during initial assessment visit)

Study Arms (1)

NSCLBP Patients

Patients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP). Participants will undergo assessment of lumbar motor control using a pressure biofeedback unit in two positions (crock lying and prone). Additionally, radiographic imaging will be performed to measure lumbopelvic parameters, including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordotic angle (LLA), to analyze their correlation with motor control dysfunction.

Diagnostic Test: Pressure biofeedback assessment

Interventions

Pressure biofeedback assessment DIAGNOSTIC_TEST

Participants will be assessed for lumbar motor control using a pressure biofeedback unit (PBU) during the Abdominal Draw-In Maneuver (ADIM) in both crock lying and prone positions. This is a non-invasive test to evaluate deep core muscle function (TrA and MF) in patients with NSCLBP. No therapeutic intervention will be administered.

NSCLBP Patients

Eligibility Criteria

• Age: 20 Years - 40 Years
• Gender Eligibility Details: Both males and females with NSCLBP are eligible to participate based on biological sex.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP), recruited from the outpatient physical therapy clinic of Cairo University. Participants will be screened based on clinical and radiographic criteria to ensure eligibility and safety.

You may qualify if:

• Patients diagnosed with non-specific chronic low back pain (NSCLBP) for more than 3 months
• Age between 20 and 40 years
• Both males and females
• Body mass index (BMI) between 18.5 and 29.9
• No physical therapy or medical treatment during the last 3 months
• Able and willing to provide informed consent

You may not qualify if:

• Patients with specific causes of low back pain (e.g., disc herniation, fractures, tumors, infections)
• History of spinal or lower limb surgery or injury
• Radiculopathy or neurological disorders affecting motor control
• Diagnosed spinal deformities (e.g., scoliosis, spondyloarthropathy, ankylosing spondylitis)
• Contraindications to X-ray (e.g., pregnancy)
• Patients currently undergoing physical therapy or medical intervention

Sponsors & Collaborators

• Mohammad Abdelazeem Darwish Saad: lead

Related Publications (1)

• Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LC, Ostelo RW, Macedo LG. Motor control exercise for chronic non-specific low-back pain. Cochrane Database Syst Rev. 2016 Jan 8;2016(1):CD012004. doi: 10.1002/14651858.CD012004.

  PMID: 26742533 BACKGROUND

Study Officials

• Enas Fawzy Youssef, Phd,MSc,PSc

  Cairo university- Faculty of physical therapy

  PRINCIPAL INVESTIGATOR

• Nevien Ezzat Elliethy, Phd,MSc,PSc

  Cairo university- faculty of medicine,department of radiology

  PRINCIPAL INVESTIGATOR

• Tasneem Ehab Mohammad, Phd,MSc,PSc

  Cairo university- Faculty of physical therapy

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohammad Abdelazeem Saad, MSc, BSc

CONTACT

01008926933; Saad.mohabd@gmail.com

Mahmoud Mohammad Ali, Phd,MSc,PSc

CONTACT

01097246005

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Correlation between motor control dysfunction and radiographic parameter in non specific chronic low back pain

Study Record Dates

• First Submitted: May 30, 2025
• First Posted: June 10, 2025
• Study Start: June 1, 2025
• Primary Completion: June 30, 2025
• Study Completion: July 30, 2025
• Last Updated: June 10, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share