Adherence to Anti-rabies Post-exposure Prophylactic Protocols

NCT07012083 | Completed

• 1 other identifier: post exposure anti-rabies
• Study Type: observational
• Target: 214
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate physicians' adherence to Advisory Committee on Immunization Practices (ACIP) guidelines regarding Anti-rabies post-exposure prophylaxis in Egypt.

Conditions

Rabies

Outcome Measures

Primary Outcomes (1)

• Adherence to Anti-rabies PEP Guidelines

  This study aims to investigate physicians' adherence to the Advisory Committee on Immunization. Practices (ACIP) guidelines regarding Anti-rabies post-exposure prophylaxis in Egypt. This will be through a score given for the correct response to the case-based questionnaire. This questionnaire include 10 case-based scenarios where anti-rabies post-exposure prophylaxis may or may not be indicated as per ACIP guidelines. True response will be scored 1, wrong response will be scored 0 with maximum total score of 10. Higher score reflects better adherence to guidelines recommendations \& vice versa.

  6 months

Secondary Outcomes (1)

• Health & Economic burden of such malpractice

  9 months

Interventions

survey OTHER

This cross-sectional survey study will be conducted on a consecutive sample of physicians who treat patients with animal bites potentially requiring post-exposure anti-rabies prophylaxis. The sample will include emergency physicians, general practice or family physicians, and surgeons of both sexes, with varying degrees of experience and post-graduate clinical training. All participants will consent to submit an anonymous Google Form-based questionnaire. The designed questionnaire will include introductory personal, academic, and work experience data about the physicians as gender, age, specialty, workplace, highest achieved medical-academic or training degree, and number of years of postgraduate clinical work experience. Candidates will be asked to reflect on their pre and postgraduate education/training quality and their confidence level in prescribing anti-rabies post-exposure prophylaxis treatment. (as a linear scale).

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This cross-sectional survey study will be conducted on a consecutive sample of physicians who treat patients with animal bites potentially requiring post-exposure anti-rabies prophylaxis. The sample will include emergency physicians, general practice or family physicians, and surgeons of both sexes, with varying degrees of experience and post-graduate clinical training.

You may qualify if:

• Physicians who treat patients with animal bites potentially requiring post-exposure anti-rabies prophylaxis. The sample will include emergency physicians, general practice or family physicians, and surgeons of both sexes, with varying degrees of experience and post-graduate clinical training.

You may not qualify if:

• Incomplete record filling

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Faculty of Medicine Tanta university

Tanta, Gharbia Governorate, Egypt

Location

Related Publications (3)

• Catherine M Brown, Alfred DeMaria. Indications for post-exposure rabies prophylaxis In: UpToDate, Connor RF (Ed), Wolters Kluwer. (Accessed on Oct 15, 2024).

  BACKGROUND

• Protocol for a well-performed rabies post-exposure prophylaxis delivery: To read along with the decision trees, 1- Wound Risk Assessment and 2 - PEP Risk Assessment. Geneva: World Health Organization; 2024. https://doi.org/10.2471/ B09018.

  BACKGROUND

• Rupprecht CE, Briggs D, Brown CM, Franka R, Katz SL, Kerr HD, Lett SM, Levis R, Meltzer MI, Schaffner W, Cieslak PR; Centers for Disease Control and Prevention (CDC). Use of a reduced (4-dose) vaccine schedule for postexposure prophylaxis to prevent human rabies: recommendations of the advisory committee on immunization practices. MMWR Recomm Rep. 2010 Mar 19;59(RR-2):1-9.

  PMID: 20300058 BACKGROUND

MeSH Terms

Conditions

Rabies

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Rhabdoviridae Infections; Mononegavirales Infections; RNA Virus Infections; Virus Diseases; Infections

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Emergency Medicine

Study Record Dates

• First Submitted: May 20, 2025
• First Posted: June 10, 2025
• Study Start: June 1, 2025
• Primary Completion: January 31, 2026
• Study Completion: March 1, 2026
• Last Updated: March 30, 2026

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)