NCT07008209

Brief Summary

The goal of this clinical trial is to learn which reappraisal strategy works better to reduce sadness and anxiety in emerging adults. The main questions it aims to answer are: What is the effect of emotion regulation strategies (reconstrual, repurposing) on short term negative emotions (anxiety, sadness)? Does the effectiveness of these strategies vary depending on the type of emotion (anxiety vs. sadness)? Are reconstrual and repurposing more effective compared to active and passive control conditions? What is the effect of these strategies on short-term positive emotions (e.g., hope, happiness)? Researchers will compare reconstrual and repurposing strategies to see which one is more effective in improving emotional outcomes. Participants will: be randomly assigned to one of eight conditions in a 4 (Regulation Strategy: Reconstrual, Repurposing, Active Control, Passive Control) × 2 (Emotion Type: Sadness vs. Anxiety) factorial design. Complete online tasks and surveys about their emotions

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
233

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 29, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 6, 2025

Completed
4 months until next milestone

Study Start

First participant enrolled

September 21, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 5, 2026

Completed
5 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 10, 2026

Completed
Last Updated

March 27, 2026

Status Verified

May 1, 2025

Enrollment Period

4 months

First QC Date

May 29, 2025

Last Update Submit

March 23, 2026

Conditions

Keywords

emotion regulationreappraisalcognitive reappraisalrepurposingreconstrualanxietysadnessemerging adults

Outcome Measures

Primary Outcomes (2)

  • Change in Negative Affect

    (VAS; scale 0-100) Participants rate how intensely they feel a target negative emotion (sadness or anxiety) using a Visual Analogue Scale (VAS) from 0 ("Not at all") to 100 ("Extremely"). Assessment Points: Time 1: After reading the emotionally evocative vignette (baseline). Time 2: After completing the assigned emotion regulation strategy (post-intervention)

    Immediately after vignette exposure vs. immediately after intervention

  • Change in valence and arousal

    Self-Assessment Manikin (SAM) ratings \[Time Frame: Before vs. after intervention\] A nonverbal pictorial measure of emotional response that assesses two dimensions: Valence (pleasant-unpleasant) Arousal (high-low) on a 1-9 scale

    Immediately after vignette exposure vs. immediately after intervention

Secondary Outcomes (3)

  • Change in Positive Affect

    Immediately after vignette exposure vs. immediately after intervention

  • PHQ-9 (Patient Health Questionnaire)

    Baseline

  • GAD-7 (Generalized Anxiety Disorder Scale)

    Baseline

Study Arms (8)

Sadness - Reconstrual

EXPERIMENTAL

Participants in this arm are exposed to sadness-related scenario and trained to use the reconstrual strategy, which involves reinterpreting the meaning of the situation to reduce negative emotions. Training is delivered online via Qualtrics and includes practice vignette. After training, participants apply reconstrual to the scenario to regulate their emotional response.

Behavioral: Reconstrual Strategy Training

Sadness - Repurposing

EXPERIMENTAL

Participants view sadness-related scenario and receive training in repurposing, which focuses on changing the goal to alleviate negative feelings. Training and practice exercises are provided online through Qualtrics before applying the strategy to the scenario.

Behavioral: Repurposing Strategy Training

Sadness - Active Control

ACTIVE COMPARATOR

Participants are presented with sadness-related scenario followed by a writing distraction task designed to divert attention from negative emotions. This arm controls for the effect of engaging in an active cognitive task unrelated to emotion regulation.

Behavioral: Active Control

Sadness - Passive Control

NO INTERVENTION

Participants view sadness-related scenario but do not receive any emotion regulation training or distraction tasks. This arm serves as a baseline to measure natural emotional change over time.

Anxiety - Reconstrual

EXPERIMENTAL

Participants are trained in reconstrual to reinterpret and reduce the perceived threat or negative appraisal of the situation and exposed to anxiety-inducing scenario. The online training includes practice vignette, followed by application of the strategy to the scenario.

Behavioral: Reconstrual Strategy Training

Anxiety - Repurposing

EXPERIMENTAL

Participants view anxiety-related scenarios and receive training in repurposing, which focuses on changing the goal to alleviate negative feelings. Training and practice exercises are provided online through Qualtrics before applying the strategy to the scenario.

Behavioral: Repurposing Strategy Training

Anxiety - Active Control

ACTIVE COMPARATOR

Participants are presented with anxiety-related scenario followed by a writing distraction task designed to divert attention from negative emotions. This arm controls for the effect of engaging in an active cognitive task unrelated to emotion regulation.

Behavioral: Active Control

Anxiety - Passive Control

NO INTERVENTION

Participants view anxiety-related scenario but do not receive any emotion regulation training or distraction tasks. This arm serves as a baseline to measure natural emotional change over time.

Interventions

Participants receive training in the reconstrual strategy, which involves recognizing and reinterpreting initial negative appraisals of emotionally challenging situations. The training guides participants to: Identify the situation and their initial negative interpretation. Generate alternative, balanced explanations that reduce negative emotional impact. The goal is to help participants view events from a different, realistic perspective to decrease negative emotions by modifying how they interpret situations.

Anxiety - ReconstrualSadness - Reconstrual

Participants receive training in the repurposing strategy, which involves adjusting or replacing personal goals to better align with the current situation. The training guides participants to: Identify the situation and the original goal that was not met. Develop alternative, realistic goals or modify existing ones to reduce the emotional impact of unmet expectations. This approach helps participants manage negative emotions by creating meaningful, adaptable goals that fit the reality of the situation.

Anxiety - RepurposingSadness - Repurposing
Active ControlBEHAVIORAL

Participants are asked to carefully copy a neutral descriptive passage without making any changes, focusing solely on transcription accuracy. This task serves as an active control by engaging participants in a cognitive task that requires attention and effort, but does not involve emotion regulation strategies. The task controls for the effects of engagement and time spent on a task without influencing participants' emotional processing.

Anxiety - Active ControlSadness - Active Control

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Aged 18-30 years
  • Fluent in Turkish
  • No current psychiatric treatment or diagnosis (self-reported)
  • Willingness to participate and provide informed consent

You may not qualify if:

  • History of severe psychiatric or neurological disorders
  • Current substance use disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ibn Haldun University

Istanbul, Turkey (Türkiye)

Location

Related Publications (6)

  • Samson AC, Kreibig SD, Soderstrom B, Wade AA, Gross JJ. Eliciting positive, negative and mixed emotional states: A film library for affective scientists. Cogn Emot. 2016 Aug;30(5):827-56. doi: 10.1080/02699931.2015.1031089. Epub 2015 May 1.

    PMID: 25929696BACKGROUND
  • Kam JWY, Wan-Sai-Cheong L, Zuk AAO, Mehta A, Dixon ML, Gross JJ. A brief reappraisal intervention leads to durable affective benefits. Emotion. 2024 Oct;24(7):1676-1688. doi: 10.1037/emo0001391. Epub 2024 Jun 20.

    PMID: 38900559BACKGROUND
  • Uusberg A, Yih J, Taxer JL, Christ NM, Toms T, Uusberg H, Gross JJ. Appraisal shifts during reappraisal. Emotion. 2023 Oct;23(7):1985-2001. doi: 10.1037/emo0001202. Epub 2023 Feb 6.

    PMID: 36745065BACKGROUND
  • Wang K, Goldenberg A, Dorison CA, Miller JK, Uusberg A, Lerner JS, Gross JJ, Agesin BB, Bernardo M, Campos O, Eudave L, Grzech K, Ozery DH, Jackson EA, Garcia EOL, Drexler SM, Jurkovic AP, Rana K, Wilson JP, Antoniadi M, Desai K, Gialitaki Z, Kushnir E, Nadif K, Bravo ON, Nauman R, Oosterlinck M, Pantazi M, Pilecka N, Szabelska A, van Steenkiste IMM, Filip K, Bozdoc AI, Marcu GM, Agadullina E, Adamkovic M, Roczniewska M, Reyna C, Kassianos AP, Westerlund M, Ahlgren L, Pontinen S, Adetula GA, Dursun P, Arinze AI, Arinze NC, Ogbonnaya CE, Ndukaihe ILG, Dalgar I, Akkas H, Macapagal PM, Lewis S, Metin-Orta I, Foroni F, Willis M, Santos AC, Mokady A, Reggev N, Kurfali MA, Vasilev MR, Nock NL, Parzuchowski M, Espinoza Barria MF, Vranka M, Kohlova MB, Ropovik I, Harutyunyan M, Wang C, Yao E, Becker M, Manunta E, Kaminski G, Boudesseu J, Marko D, Evans K, Lewis DMG, Findor A, Landry AT, Aruta JJB, Ortiz MS, Vally Z, Pronizius E, Voracek M, Lamm C, Grinberg M, Li R, Valentova JV, Mioni G, Cellini N, Chen SC, Zickfeld J, Moon K, Azab H, Levy N, Karababa A, Beaudry JL, Boucher L, Collins WM, Todsen AL, van Schie K, Vintr J, Bavolar J, Kaliska L, Krizanic V, Samojlenko L, Pourafshari R, Geiger SJ, Beitner J, Warmelink L, Ross RM, Stephen ID, Hostler TJ, Azouaghe S, McCarthy R, Szala A, Grano C, Solorzano CS, Anjum G, Jimenez-Leal W, Bradford M, Perez LC, Cruz Vasquez JE, Galindo-Caballero OJ, Vargas-Nieto JC, Kacha O, Arvanitis A, Xiao Q, Carcamo R, Zorjan S, Tajchman Z, Vilares I, Pavlacic JM, Kunst JR, Tamnes CK, von Bastian CC, Atari M, Sharifian M, Hricova M, Kacmar P, Schrotter J, Rahal RM, Cohen N, FatahModares S, Zrimsek M, Zakharov I, Koehn MA, Esteban-Serna C, Calin-Jageman RJ, Krafnick AJ, Strukelj E, Isager PM, Urban J, Silva JR, Martoncik M, Ocovaj SB, Sakan D, Kuzminska AO, Djordjevic JM, Almeida IAT, Ferreira A, Lazarevic LB, Manley H, Ricaurte DZ, Monteiro RP, Etabari Z, Musser E, Dunleavy D, Chou W, Godbersen H, Ruiz-Fernandez S, Reeck C, Batres C, Kirgizova K, Muminov A, Azevedo F, Alvarez DS, Butt MM, Lee JM, Chen Z, Verbruggen F, Ziano I, Tumer M, Charyate ACA, Dubrov D, Tejada Rivera MDCMC, Aberson C, Palfi B, Maldonado MA, Hubena B, Sacakli A, Ceary CD, Richard KL, Singer G, Perillo JT, Ballantyne T, Cyrus-Lai W, Fedotov M, Du H, Wielgus M, Pit IL, Hruska M, Sousa D, Aczel B, Hajdu N, Szaszi B, Adamus S, Barzykowski K, Micheli L, Schmidt ND, Zsido AN, Paruzel-Czachura M, Muda R, Bialek M, Kowal M, Sorokowska A, Misiak M, Mola D, Ortiz MV, Correa PS, Belaus A, Muchembled F, Ribeiro RR, Arriaga P, Oliveira R, Vaughn LA, Szwed P, Kossowska M, Czarnek G, Kielinska J, Antazo B, Betlehem R, Stieger S, Nilsonne G, Simonovic N, Taber J, Gourdon-Kanhukamwe A, Domurat A, Ihaya K, Yamada Y, Urooj A, Gill T, Cadek M, Bylinina L, Messerschmidt J, Kurfali M, Adetula A, Baklanova E, Albayrak-Aydemir N, Kappes HB, Gjoneska B, House T, Jones MV, Berkessel JB, Chopik WJ, Coksan S, Seehuus M, Khaoudi A, Bokkour A, El Arabi KA, Djamai I, Iyer A, Parashar N, Adiguzel A, Kocalar HE, Bundt C, Norton JO, Papadatou-Pastou M, De la Rosa-Gomez A, Ankushev V, Bogatyreva N, Grigoryev D, Ivanov A, Prusova I, Romanova M, Sarieva I, Terskova M, Hristova E, Kadreva VH, Janak A, Schei V, Sverdrup TE, Askelund AD, Pineda LMS, Krupic D, Levitan CA, Johannes N, Ouherrou N, Say N, Sinkolova S, Janjic K, Stojanovska M, Stojanovska D, Khosla M, Thomas AG, Kung FYH, Bijlstra G, Mosannenzadeh F, Balci BB, Reips UD, Baskin E, Ishkhanyan B, Czamanski-Cohen J, Dixson BJW, Moreau D, Sutherland CAM, Chuan-Peng H, Noone C, Flowe H, Anne M, Janssen SMJ, Topor M, Majeed NM, Kunisato Y, Yu K, Daches S, Hartanto A, Vdovic M, Anton-Boicuk L, Forbes PAG, Kamburidis J, Marinova E, Nedelcheva-Datsova M, Rachev NR, Stoyanova A, Schmidt K, Suchow JW, Koptjevskaja-Tamm M, Jernsather T, Olofsson JK, Bialobrzeska O, Marszalek M, Tatachari S, Afhami R, Law W, Antfolk J, Zuro B, Van Doren N, Soto JA, Searston R, Miranda J, Damnjanovic K, Yeung SK, Krupic D, Hoyer K, Jaeger B, Ren D, Pfuhl G, Klevjer K, Corral-Frias NS, Frias-Armenta M, Lucas MY, Torres AO, Toro M, Delgado LGJ, Vega D, Solas SA, Vilar R, Massoni S, Frizzo T, Bran A, Vaidis DC, Vieira L, Paris B, Capizzi M, Coelho GLH, Greenburgh A, Whitt CM, Tullett AM, Du X, Volz L, Bosma MJ, Karaarslan C, Sarioguz E, Allred TB, Korbmacher M, Colloff MF, Lima TJS, Ribeiro MFF, Verharen JPH, Karekla M, Karashiali C, Sunami N, Jaremka LM, Storage D, Habib S, Studzinska A, Hanel PHP, Holford DL, Sirota M, Wolfe K, Chiu F, Theodoropoulou A, Ahn ER, Lin Y, Westgate EC, Brohmer H, Hofer G, Dujols O, Vezirian K, Feldman G, Travaglino GA, Ahmed A, Li M, Bosch J, Torunsky N, Bai H, Manavalan M, Song X, Walczak RB, Zdybek P, Friedemann M, Rosa AD, Kozma L, Alves SG, Lins S, Pinto IR, Correia RC, Babincak P, Banik G, Rojas-Berscia LM, Varella MAC, Uttley J, Beshears JE, Thommesen KK, Behzadnia B, Geniole SN, Silan MA, Maturan PLG, Vilsmeier JK, Tran US, Izquierdo SM, Mensink MC, Sorokowski P, Groyecka-Bernard A, Radtke T, Adoric VC, Carpentier J, Ozdogru AA, Joy-Gaba JA, Hedgebeth MV, Ishii T, Wichman AL, Roer JP, Ostermann T, Davis WE, Suter L, Papachristopoulos K, Zabel C, Onie S, Ebersole CR, Chartier CR, Mallik PR, Urry HL, Buchanan EM, Coles NA, Primbs MA, Basnight-Brown DM, IJzerman H, Forscher PS, Moshontz H. A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic. Nat Hum Behav. 2021 Aug;5(8):1089-1110. doi: 10.1038/s41562-021-01173-x. Epub 2021 Aug 2.

    PMID: 34341554BACKGROUND
  • Uusberg A, Ford B, Uusberg H, Gross JJ. Reappraising reappraisal: an expanded view. Cogn Emot. 2023 May-Jun;37(3):357-370. doi: 10.1080/02699931.2023.2208340. Epub 2023 May 10.

    PMID: 37161355BACKGROUND
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    PMID: 26172497BACKGROUND

MeSH Terms

Conditions

Anxiety DisordersDepressionEmotional Regulation

Condition Hierarchy (Ancestors)

Mental DisordersBehavioral SymptomsBehaviorSelf-ControlSocial Behavior

Study Officials

  • Ayşe ALTAN-ATALAY, Assoc. Prof. Dr

    Kadir Has University

    PRINCIPAL INVESTIGATOR
  • Burcu UYSAL, Assoc. Prof. Dr

    Ibn Haldun University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Masking Details
This study used an online platform (Qualtrics) to assign participants randomly to study arms and deliver interventions. Investigators are blinded to group allocation. Investigators do not have access to or control over assignment information during data collection, ensuring masking (single-blind design).
Purpose
BASIC SCIENCE
Intervention Model
FACTORIAL
Model Details: This study uses a 2 (Emotion Type: Sadness vs. Anxiety) × 4 (Strategy Type: Reconstrual, Repurposing, Active Control, Passive Control) between-subjects factorial design. Participants are randomly assigned to one of eight experimental groups. Each participant is exposed to an emotionally evocative scenario (either sadness or anxiety), followed by an intervention based on their assigned strategy condition. The aim is to examine the main and interaction effects of strategy type and emotion type on changes in emotional experience before and after the intervention. Study Type: Interventional Design: Randomized, 2 × 4 between-subject factorial design Factors: Emotion Type (Sadness vs. Anxiety) × Strategy (Reconstrual, Repurposing, Active Control, Passive Control) Within-Subjects: Time (Post-Scenario vs. Post-Intervention) Allocation: Randomized Masking: Single-blind Primary Purpose: Basic Science
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD(c)

Study Record Dates

First Submitted

May 29, 2025

First Posted

June 6, 2025

Study Start

September 21, 2025

Primary Completion

January 5, 2026

Study Completion

January 10, 2026

Last Updated

March 27, 2026

Record last verified: 2025-05

Locations