Can the Ergometric Test in Flu-like Syndrome Help in the Outcome Analysis of Unvaccinated Patients

NCT07007377 | Completed DMC

• 1 other identifier: Clínica Pró-Coração
• Study Type: observational
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

During the flu-like syndrome, the cardiovascular risk is increased, especially in the elderly. Understanding whether blood pressure assessment during an exercise test can aid in the understanding of patient outcomes, thereby improving prognostic ability in clinical practice, is the focus of the present study. Therefore, the aim of this study is to evaluate the hemodynamic response of adults with flu-like symptoms, both vaccinated and unvaccinated, and to conduct a 30-day follow-up for assessment. Patients who are indicated for an ergometric test and present with flu-like syndrome will be selected. We will inquire about their vaccination history and perform the ergometric test to evaluate test duration, arrhythmias, and ischemias

Conditions

Flu-like Syndrome; FLU; Flu-like Symptoms; Vaccination

Outcome Measures

Primary Outcomes (1)

• Can the ergometric test in flu-like syndrome help in the outcome analysis of unvaccinated patients?

  The investigators will analyze whether different responses to exertion, such as blood pressure disorders, are more evident in individuals with or without symptoms who have or have not been vaccinated.

  1 month

Secondary Outcomes (1)

• Symptoms

  7 and 14 days after treadmill exercise test

Study Arms (2)

Vaccinated

Vaccinated subjects

Other: Follow-up

Non-vaccinated

Non-vaccinated subjects

Other: Follow-up

Interventions

Follow-up OTHER

Follow-up

Non-vaccinated; Vaccinated

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults with flu symptoms, which were vaccinated or not.

You may qualify if:

• flu-symptoms

You may not qualify if:

• recent orthopedic surgery

Sponsors & Collaborators

• University of Sao Paulo: lead

Study Sites (1)

Clínica Pró-Coração

São Paulo, São Paulo, 05021010, Brazil

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD, Post-doctoral student, Manager of research from Clinica Pró-Coração

Study Record Dates

• First Submitted: March 27, 2025
• First Posted: June 5, 2025
• Study Start: April 1, 2025
• Primary Completion: August 29, 2025
• Study Completion: December 5, 2025
• Last Updated: May 19, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)