Anatomical Landmarks for Chest Wall Perforators Used for Partial Breast Reconstruction

NCT07006662 | Not Yet Recruiting

• 1 other identifier: 3427
• Study Type: observational
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this 6-month proof-of-concept study is to map out the chest wall perforators in relation to anatomical landmarks for partial breast reconstruction.

Conditions

Breast Cancer Female

Outcome Measures

Primary Outcomes (4)

• Location of vesselse

  The location of the AICAP vessels in vertical and horizontal axis using constant bony and soft tissue landmarks. This will be measured by the distance of the perforators from the anatomical landmarks

  6 months

• Location of vessels

  The location of the MICAP vessels in vertical and horizontal axis using constant bony and soft tissue landmarks. This will be measured by the distance of the perforators from the anatomical landmarks

  6 months

• Location of vessels

  The location of the LTAP vessels in vertical and horizontal axis using constant bony and soft tissue landmarks. This will be measured by the distance of the perforators from the anatomical landmarks

  6 months

• Location of vessels

  The location of the LICAP vessels in vertical and horizontal axis using constant bony and soft tissue landmarks. This will be measured by the distance of the perforators from the anatomical landmarks

  6 months

Secondary Outcomes (1)

• Variability

  6 months

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The trial will be carried out at University Hospitals of North Midlands (UHNM). This will be a single centre study. Patients will be screened by the breast surgery Team for the eligibility criteria and recruited from the Breast Outpatients Clinic and marking of the perforators will be carried out on admission unit.

You may qualify if:

• Patients undergoing elective breast surgery
• Age ≥ 18 years
• Female
• BMI ≤ 30 kg/m2
• Willing and able to give fully informed consent,
• Willing and able to comply with the study procedures

You may not qualify if:

• Pregnant patients
• Previous bilateral Breast or axillary surgery
• Undergoing bilateral oncoplastic procedure or requiring bilateral pre-operative marking
• Undergoing breast surgery requiring pre-operative marking of some of the landmarks and has had contralateral breast or axillary surgery in the past
• Surgery planned within 24 hours of screening for eligibility
• Known history of allergy or contact dermatitis to ultrasound gels

Sponsors & Collaborators

• University Hospitals of North Midlands NHS Trust: lead

Study Sites (1)

University Hospitals of North Midlands NHS Trust

Stoke-on-Trent, ST4 6QG, United Kingdom

Location

Central Study Contacts

Aviva Ogbolosingha

CONTACT

01782675380; aviva.ogbolosingha@uhnm.nhs.uk

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 27, 2025
• First Posted: June 5, 2025
• Study Start: April 1, 2026
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: February 13, 2026

Record last verified: 2026-02

Locations

GB (1)