Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion
Diagnostic and Prognostic Role of Pleural Fluid Neutrophil-to Lymphocyte and Monocyte-to-Lymphocyte Ratios in Exudative Pleural Effusion
1 other identifier
observational
60
1 country
1
Brief Summary
Exudative pleural effusion (EPE) presents a diagnostic challenge, requiring accurate biomarkers to predict outcomes and guide treatment. The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) in pleural fluid are emerging as potential prognostic markers. We aimed to assess the diagnostic and prognostic utility of pleural fluid NLR and MLR in EPE.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2025
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 11, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 25, 2025
CompletedFirst Submitted
Initial submission to the registry
May 26, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
May 26, 2025
CompletedFirst Posted
Study publicly available on registry
June 4, 2025
CompletedJune 4, 2025
May 1, 2025
14 days
May 26, 2025
May 26, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
MLR and NLR measuring in pleural fluid
counting pleural fluid monocytes,lymphocytes and neutrophils
1 month
Other Outcomes (1)
MLR and NLR measuring in pleural fluid
one month
Study Arms (1)
only one group of patients
prospective cohort randomized control study
Interventions
pleural fluid aspiration and cellular analysis
Eligibility Criteria
60 person with pleural effusion
You may qualify if:
- adult patients aged 18-80 years with an EPE diagnosis confirmed by thoracentesis.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chest Department -Faculty of Medicine
Alexandria, Egypt, 11511, Egypt
Related Links
Study Officials
- PRINCIPAL INVESTIGATOR
mohamed Sabry eltarhony, lecturer
Alexandria University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Lecturer of chest diseases
Study Record Dates
First Submitted
May 26, 2025
First Posted
June 4, 2025
Study Start
May 11, 2025
Primary Completion
May 25, 2025
Study Completion
May 26, 2025
Last Updated
June 4, 2025
Record last verified: 2025-05
Data Sharing
- IPD Sharing
- Will not share
not in the policy of the department