Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery

NCT07001670 | Active Not Recruiting

• 1 other identifier: IUC-FTR-RK-01
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized controlled clinical trial aims to evaluate the effects of an 8-week tele-yoga intervention in individuals with lung cancer who have undergone lung resection surgery. The intervention group will receive supervised yoga sessions via online synchronous video conferencing, while the control group will continue with standard post-operative care. The primary outcome is exercise capacity (6-minute walk test), with secondary outcomes including pulmonary function, respiratory and peripheral muscle strength, physical activity level, dyspnea, fatigue, sleep quality, anxiety and depression, and quality of life. It is hypothesized that tele-yoga will improve physical and psychological recovery post-surgery and may serve as a feasible home-based pulmonary rehabilitation alternative.

Conditions

Postoperative Period; Lung Cancer (Diagnosis)

Keywords

Exercise capacity; Pulmonary function; Muscle Strength; Dyspnea; Fatigue; Anxiety; Depression; Quality of Life; Exercise Therapy; Telemedicine; Rehabilitation

Outcome Measures

Primary Outcomes (1)

• The Six-Minute Walk Test (6MWT)

  Distance walked in six minutes will be recorded. Test will be conducted according to the guideline of American Thoracic Society. Functional exercise capacity will be evaluated with the six-minute walk test. Patients will be walked in a 30-meter-long corridor for 6 minutes and the maximum walking distance will be measured. Before and after the test, heart rate, blood pressure and O2 saturation will be measured with pulse oximetry, and dyspnea and fatigue levels will be determined according to the Modified Borg scale.

  Change from Baseline at 8 weeks

Secondary Outcomes (12)

• Incremental Shuttle Walk Test (ISWT)

  Change from Baseline at 8 weeks

• 6-Minute Pegboard and Ring Test (6PBRT)

  Change from Baseline at 8 weeks

• Pulmonary Function Tests (PFT)

  Change from Baseline at 8 weeks

• Respiratory Muscle Strength Test (MIP/MEP)

  Change from Baseline at 8 weeks

• Peripheral Muscle Strength (Handgrip Strength Test)

  Change from Baseline at 8 weeks

Study Arms (2)

Tele-Yoga Group

EXPERIMENTAL

Participants in this arm will receive an 8-week supervised tele-yoga program delivered via real-time video conferencing.

Other: Tele-Yoga Training

Control Group

NO INTERVENTION

The control group will not receive any intervention.

Interventions

Tele-Yoga Training OTHER

The Tele-yoga group will participate in real-time yoga sessions three times a week for eight weeks, including individual sessions for the first two weeks and small group sessions for the remaining six weeks, with all sessions supervised by a certified instructor. Each session will last approximately 45-60 minutes and include a 5-10 minute warm-up, 15-20 minutes of yoga postures, 15-20 minutes of yogic breathing exercises, and 5-10 minutes of relaxation and meditation.

Tele-Yoga Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged between 18 and 65 years,
• Histologically confirmed diagnosis of Stage I-IIIA lung cancer according to the 9th edition of the AJCC Cancer Staging Manual,
• Underwent lobectomy, pneumonectomy, segmentectomy, or wedge resection via thoracotomy or video-assisted thoracoscopic surgery (VATS),
• An estimated life expectancy of ≥6 months,
• Karnofsky Performance Status score greater than 80% at study entry,
• Possession of the necessary equipment and access to a stable internet connection to enable participation in online interventions.

You may not qualify if:

• History of receiving radiotherapy or chemotherapy prior to surgery,
• Presence of severe dysfunction in vital organs such as the heart, brain, kidneys, or others,
• Having any comorbid condition that contraindicates participation in an exercise training program,
• Presence of serious postoperative complications,
• Cognitive impairments that hinder effective communication,
• Current participation in a structured and regular exercise program,
• Missing three consecutive weeks of sessions or completing less than 75% of the prescribed exercises,
• Voluntary withdrawal from the study by the participant.

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Department of Thoracic Surgery, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Lung Neoplasms; Disease; Dyspnea; Fatigue; Anxiety Disorders; Depression

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms; Mental Disorders; Behavioral Symptoms; Behavior

Study Officials

• Rengin Demir, Prof

  Istanbul University - Cerrahpasa

  PRINCIPAL INVESTIGATOR

• Akif Turna, Prof

  Istanbul University - Cerrahpasa

  PRINCIPAL INVESTIGATOR

• Sevde B Kara, PhD student

  Istanbul University - Cerrahpasa

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Outcome assessments will be performed by an investigator who is blinded to group allocation.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 23, 2025
• First Posted: June 3, 2025
• Study Start: June 10, 2025
• Primary Completion (Estimated): June 10, 2026
• Study Completion (Estimated): July 10, 2026
• Last Updated: December 18, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)