Improving Uptake of Surveillance in Colorectal Cancer Survivors Through Navigation and Web Education
A Pilot Trial to Evaluate the Effectiveness of Navigation, Interactive Web Education, or the Combination of Both to Promote Guideline-Concordant Colorectal Cancer Surveillance Care
3 other identifiers
interventional
75
1 country
2
Brief Summary
This pilot clinical trial looks at whether patient navigation services, an interactive web education intervention, called Current Together After Cancer (CTAC), or both navigation and CTAC works to improve the uptake of surveillance in patients with stage I-III colorectal cancer (CRC). Post-treatment surveillance is critical to detect recurrence early, yet many CRC survivors do not receive recommended surveillance care. Surveillance is a complex process that includes laboratory tests, cross-sectional imaging, and endoscopic procedures. Patient navigation services, interactive web education, or a combination of both may improve surveillance care for patients with stage I-III colorectal cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Nov 2025
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 21, 2025
CompletedFirst Posted
Study publicly available on registry
May 30, 2025
CompletedStudy Start
First participant enrolled
November 17, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 31, 2027
February 20, 2026
February 1, 2026
1.4 years
May 21, 2025
February 18, 2026
Conditions
Outcome Measures
Primary Outcomes (2)
Completion of colonoscopy (stage I colorectal carcinoma patients)
Up to 18 months post-surgical resection
Completing any colonoscopy, carcinoembryonic antigen tumor marker (CEA), and cross-sectional imaging (stage II-III colorectal carcinoma patients)
Will compare rates of surveillance care completion 1-year (up to 18 months accounting for delays that may be due to inability accessing endoscopy) post-surgical resection across groups using chi-square tests. Will use a multivariable logistic regression model to test for factors that may be associated with increased or decreased surveillance care including patient-level demographic factors (e.g., age, sex, etc.) and available clinic-level factors (e.g., clinic size, etc.).
Up to 18 months post-surgical resection
Secondary Outcomes (5)
Knowledge of colorectal cancer (CRC) surveillance
At baseline, and 3 months post enrollment
Self-efficacy to complete CRC surveillance
At baseline, and 3 months post enrollment
Acceptability of the intervention
At 3 months post enrollment
Intervention appropriateness
At 3 months post enrollment
Feasibility of the intervention
At 3 months post enrollment
Study Arms (3)
Arm A (navigation)
EXPERIMENTALPatients at the Virginia Mason clinic location receive access to navigation services, in person, via telephone or via electronic conferencing platform, including education on surveillance care, reminders to complete care and assistance in scheduling surveillance, within 3 months of standard of care surgical resection.
Arm B (CTAC)
EXPERIMENTALPatients at the Fred Hutch (South Lake Union) clinic location receive access to the online CTAC intervention, which includes self-directed, interactive education about surveillance and a checklist of care, within 3 months of standard of care surgical resection.
Arm C (navigation and CTAC)
EXPERIMENTALPatients at the Fred Hutch (Overlake + Evergreen) clinic location receive access to navigation services, in person, via telephone or via electronic conferencing platform, including education on surveillance care, reminders to complete care and assistance in scheduling surveillance, and access to the online CTAC intervention, which includes self-directed, interactive education about surveillance and a checklist of care, within 3 months of standard of care surgical resection.
Interventions
Ancillary studies
Receive patient navigation services
Ancillary studies
Complete self-directed interactive education
Eligibility Criteria
You may qualify if:
- Age ≥ 18 due to disease and clinic population
- Stage I-III CRC survivor within 3 months post-surgical resection
- Being seen at a participating clinic
- Ability to understand and complete surveys in English
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Benaroya Research Institute at Virginia Mason
Seattle, Washington, 98101, United States
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Rachel B. Issaka, MD, MAS
Fred Hutch/University of Washington Cancer Consortium
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 21, 2025
First Posted
May 30, 2025
Study Start
November 17, 2025
Primary Completion (Estimated)
March 31, 2027
Study Completion (Estimated)
March 31, 2027
Last Updated
February 20, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will not share