Normative Data for Sweating Rate, Sweat Sodium Concentration and Sweat Sodium Loss in Female Athlete

NCT06995768 | Recruiting

• 1 other identifier: PEP-2506
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The main objectives are to determine sweat sodium concentration \[Na+\], whole body sweat rate (WBSR) and rate of sweat sodium loss (RSSL) in female athletes aged 13 and above during their normal planned training session across various sports (basketball, soccer, volleyball, cheer, flag football and softball).

Conditions

Sweat Rate

Keywords

sweat; sodium loss; sweat patch; athlete; healthy volunteer

Outcome Measures

Primary Outcomes (3)

• Regional sweat [Na+]

  Absorbent patch technique (3M TegadermTM + Pad; 3M, St. Paul, MN; pad size 10 cm2 with an absorbent capacity of \~1.3 g) to left and right dorsal arm. An additional patch on the right scapula may be added depending on the accessibility to the sites on the body and the nature of the sport. Analyzed using a HORIBA (LAQUAtwin Na-11)

  One day from start through end of a single coach-led normal training practice session. Practice duration will be dictated by coaching staff.

• Whole body sweat rate (WBSR) WBSR

  Pre- versus post body mass on scale, taking into account food and fluid intake, urine and stool output

  One day from start through end of a single coach-led training normal training practice session. Practice duration will be dictated by coaching staff.A

• Rate of sweat sodium loss (RSSL)

  The rate of sodium sweat loss (RSSL) will be determined as the product of sweat \[Na+\] and whole-body sweat rate (WBSR)

  One day from start through end of a single coach-led normal training practice session. Duration will be dictated by coaching staff.

Secondary Outcomes (3)

• Urine specific gravity (USG)

  Pre-exercise at one coach-led normal training practice session.

• Fluid intake

  One day from start through end of a single coach-led normal training practice session. Duration will be dictated by coaching staff.

• Carbohydrate intake

  One day from start through end of a single coach-led normal training practice session. Duration will be dictated by coaching staff.

Study Arms (1)

Female team sports athletes aged 13 and over

Multiple athletic teams at locations in USA and UK

Other: Sweat patch

Interventions

Sweat patch OTHER

Wear sweat patch during regular team sports practice session

Female team sports athletes aged 13 and over

Eligibility Criteria

• Age: 13 Years+
• Gender Eligibility Details: Reason female only is lack of sports science sweat research data specific to female athletes
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy female athletes in coach-led team sports

You may qualify if:

• Subject is female
• Subject is 13yrs+
• Subject has been cleared for sport participation by their personal or team physician and/or coach-led practice/training.
• Subject is participating in sport on the youth/ amateur/ collegiate/professional/elite level
• If under 18, a parental/guardian consent form will be completed.

You may not qualify if:

• As this study is undertaken at the athletes training facility, the medical staff at the team/club will advise on who should/ should not take part.
• Subject has an allergy to adhesives (e.g., experiences rash reactions to typical adhesive bandages

Sponsors & Collaborators

• PepsiCo Global R&D: lead

Study Sites (1)

Gatorade Sports Science Institute

Chicago, Illinois, 60607, United States

RECRUITING

Study Officials

• Rebecca Randell, PhD

  PepsiCo R&D Life Sciences, Sports Science

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rebecca Randell, PhD

CONTACT

414-520-7097; rebecca.randell@pepsico.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 30, 2025
• First Posted: May 29, 2025
• Study Start: April 22, 2025
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026
• Last Updated: May 29, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)