NCT06994039

Brief Summary

The consistency of EUS-PPG measurements between left lateral decubitus and supine positions is unclear. In this prospective comparative study, we are aimed to evaluate the correlation between EUS-PPG measured in supine position (EUS-suPPG), and EUS-PPG measured in left lateral decubitus position (EUS-lePPG).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jun 2025

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 20, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 29, 2025

Completed
18 days until next milestone

Study Start

First participant enrolled

June 16, 2025

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 29, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 29, 2025

Completed
Last Updated

February 6, 2026

Status Verified

May 1, 2025

Enrollment Period

7 months

First QC Date

May 20, 2025

Last Update Submit

February 4, 2026

Conditions

Left Lateral DecubitusPortal Pressure Gradient (PPG) Measurement Guided by Endoscopic Ultrasound (EUS)

Outcome Measures

Primary Outcomes (1)

  • EUS-lePPG

    EUS-PPG measured in left lateral decubitus position

    From the begining of zero calibration for pressure transducer to the end of the endoscopic procedure, until up to 1 day.

Study Arms (1)

EUS-suPPG

EUS-PPG measured in supine position

Procedure: EUS-lePPG

Interventions

EUS-lePPGPROCEDURE

EUS-PPG measured in left lateral decubitus position

EUS-suPPG

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Hospitalized patients with liver cirrhosis

You may qualify if:

  • Hospitalized patients with liver cirrhosis, and are willing to sign the informed consent.

You may not qualify if:

  • Unwilling to sign the informed consent
  • Severe coagulopathy (INR\>1.6)
  • Severe thrombocytopenia (platelets \<20,000/μL)
  • Bacteremia
  • Age\<18, or≥81
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The 2nd Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, China

Location

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 20, 2025

First Posted

May 29, 2025

Study Start

June 16, 2025

Primary Completion

December 29, 2025

Study Completion

December 29, 2025

Last Updated

February 6, 2026

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)