NCT06988345

Brief Summary

All patients with a juxtarenal abdominal aortic aneurysm who underwent open aneurysm therapy between January 2010 and July 2020 were included retrospectively.

Trial Health

53
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Longer than P75 for all trials

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
11 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
3.9 years until next milestone

First Submitted

Initial submission to the registry

November 20, 2024

Completed
6 months until next milestone

First Posted

Study publicly available on registry

May 23, 2025

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

May 23, 2025

Status Verified

May 1, 2025

Enrollment Period

11 years

First QC Date

November 20, 2024

Last Update Submit

May 15, 2025

Conditions

Juxtarenal AneurysmsOpen Repair

Outcome Measures

Primary Outcomes (2)

  • Mortality

    Mortality after 30 days postop

    30 days after intervention

  • Acute renal failure

    Acute renal failure postoperatively, defined by KDIGO criteria of AKI \[22890468\]

    30 days after intervention

Secondary Outcomes (5)

  • Dialysis

    during Follow up period, checked every year

  • Reinterventions

    during Follow up period, checked every year

  • Mortality

    during Follow up period (up to 13 years)

  • Aneurysm-related Mortality

    during Follow up period (up to 13 years)

  • Post-operative complication rates

    During Follow-up period (up to 13 years)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients with a juxtarenal aneurysm who fulfill the inclusion criteria or do not fulfill the exclusion criteria may be included in this study

You may qualify if:

  • Patients with a juxtarenal aneurysm (defined as infrarenal neck \<10mm and clamping above at least one renal artery \[31592091\])
  • Open therapy with infrarenal (Anschluss)
  • \>18 years

You may not qualify if:

  • Patients with an anastomosis above the renal arteries (e.g. including bypass to a renal artery)
  • Patients with supravisceral clamping
  • Patients with reconstruction of the aorta in the suprarenal area
  • Patients with connective tissue diseases (e.g. Marfan syndrome or Ehler Danlos syndrome)
  • Post-dissection aneurysms
  • Infected aneurysms
  • Conversions after endovascular therapy
  • Inflammatory aneurysms

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Univ.-Prof. Dr. med.

Study Record Dates

First Submitted

November 20, 2024

First Posted

May 23, 2025

Study Start

January 1, 2010

Primary Completion

December 31, 2020

Study Completion

December 31, 2025

Last Updated

May 23, 2025

Record last verified: 2025-05