Physical Impairments in Children With Chronic Renal Failure

NCT06981585 | Recruiting

• 1 other identifier: Healthy and Kidney Failure
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

When the literature is examined, it is seen that the extent to which cough strength, grip strength, physical activity level and quality of life levels are affected in children with chronic kidney failure compared to healthy children is not sufficiently clarified. For this reason, this study aimed to reveal impairments in grip strength, cough strength, physical activity, sleep quality or quality of life in children with chronic renal failure compared to healthy children.

Conditions

Chronic Kidney Failure; Chronic Kidney Diseases

Keywords

Chronic Kidney Failure; Muscle Strength; Physical Activity; Sleep Quality; Quality of Life

Outcome Measures

Primary Outcomes (1)

• Quality of life score

  The scale we will use to assess health-related quality of life, the Pediatric Quality of Life Inventory (PedsQL 4.0). The scale was developed to assess the health-related quality of life of children and adolescents between the ages of 2 and 18 and consists of physical, emotional, social and school functioning items, totaling 23 items.Scores from this questionnaire are converted to a scale of 0 to 100. Higher scores indicate better health-related quality of life.

  through study completion, an average of 1 year

Secondary Outcomes (4)

• Cough Strength

  through study completion, an average of 1 year

• Hand Grip Strength

  through study completion, an average of 1 year

• Evaluation of Physical Activities

  through study completion, an average of 1 year

• Evaluation of sleep quality

  through study completion, an average of 1 year

Study Arms (2)

Chronic Kidney Failure Group

This group will consist of children and adolescents with chronic kidney failure.

Other: Physical Evaluations of Patients with Chronic Kidney Failure

Control Group

This group will consist of healthy children and adolescents.

Other: Physical Evaluations of Healthy Children

Interventions

Physical Evaluations of Patients with Chronic Kidney Failure OTHER

In this study, data from children and adolescents with chronic kidney disease will be collected through face-to-face assessments. Grip strength, cough strength, physical activity, sleep quality and quality of life will be assessed in children and adolescents who meet the inclusion criteria. All data obtained through these assessments will be collected from participants face-to-face at one time and for a maximum of approximately 1 hour.

Chronic Kidney Failure Group

Physical Evaluations of Healthy Children OTHER

In this study, data from healthy children and adolescents will be collected through face-to-face assessments. Grip strength, cough strength, physical activity, sleep quality and quality of life will be assessed in children and adolescents who meet the inclusion criteria. Data obtained through all these assessments will be collected from participants face-to-face at once and for a maximum of approximately 1 hour.

Control Group

Eligibility Criteria

• Age: 8 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

At least 25 patients with Chronic Kidney Failure will be included in the research group and at least 25 healthy individuals will be included in the control group.

You may qualify if:

• Being between the ages of 8-18
• Being clinically stable for at least the last 3 weeks
• Having the necessary cooperation for the measurements
• Being willing to participate in the study
• Being between the ages of 8-18,
• Having the necessary cooperation for the measurements,
• Being willing to participate in the research

You may not qualify if:

• Having any orthopedic, neurological, cardiovascular or psychological problems that may prevent measurements from being taken in the last 6 months
• Being a smoker or having quit
• Having had a kidney transplant.
• Having a history of any orthopedic, neurological, cardiovascular or psychological problems that may prevent measurements from being taken in the last 6 months
• Having any chronic disease
• Being a smoker or having quit smoking

Sponsors & Collaborators

• Izmir Democracy University: lead

Study Sites (1)

İzmir Demokrasi Üniversitesi

Izmir, 35140, Turkey (Türkiye)

RECRUITING

Related Publications (3)

• Clark SL, Denburg MR, Furth SL. Physical activity and screen time in adolescents in the chronic kidney disease in children (CKiD) cohort. Pediatr Nephrol. 2016 May;31(5):801-8. doi: 10.1007/s00467-015-3287-z. Epub 2015 Dec 18.

  PMID: 26684326 BACKGROUND

• Taner S, Ekberli G, Gunes S. The Effect of Sleep Habits on Quality of Life in Pediatric Patients With Chronic Kidney Disease. Cureus. 2024 Jul 15;16(7):e64585. doi: 10.7759/cureus.64585. eCollection 2024 Jul.

  PMID: 39144881 BACKGROUND

• Darwish AH, Abdel-Nabi H. Sleep disorders in children with chronic kidney disease. Int J Pediatr Adolesc Med. 2016 Sep;3(3):112-118. doi: 10.1016/j.ijpam.2016.06.001. Epub 2016 Jun 29.

  PMID: 30805480 BACKGROUND

MeSH Terms

Conditions

Kidney Failure, Chronic; Renal Insufficiency, Chronic; Motor Activity; Sleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Mental Disorders

Study Officials

• Gülşah Barğı

  İzmir Demokrasi Üniversitesi

  STUDY DIRECTOR

• Hüseyin Kıran

  İzmir Demokrasi Üniversitesi

  PRINCIPAL INVESTIGATOR

• Nida Dinçel

  SBÜ İTF DR. BEHÇET UZ ÇOCUK HASTALIKLARI VE CERRAHİSİ EĞİTİM VE ARAŞTIRMA HASTANESİ

  STUDY DIRECTOR

Central Study Contacts

Gülşah Barğı

CONTACT

+90 232 299 0739; gulsahbargi35@gmail.com

Hüseyin Kıran

CONTACT

+90 531 706 8000; huseyinulaskiran@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: May 12, 2025
• First Posted: May 20, 2025
• Study Start: August 1, 2025
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): March 1, 2027
• Last Updated: August 28, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)