Acceptance and Commitment Therapy for Chemsex

NCT06980974 | Withdrawn

• 1 other identifier: IRB-300014764
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Quasi-randomized control trial of acceptance and commitment therapy (ACT) for chemsex.

Conditions

Chemsex

Keywords

chemsex; ACT

Outcome Measures

Primary Outcomes (1)

• Chemsex frequency

  Self-reported chemsex frequency in the past six months

  Baseline, 16 week post-treatment, six month follow-up

Secondary Outcomes (9)

• Modified NIDA ASSIST

  Baseline, 16 week post-treatment, six month follow-up

• Sexual Health History

  Baseline

• Center for epidemiologic studies depression scale

  Baseline, 16 week post-treatment, six month follow-up, every two weeks.

• generalized anxiety disorder-7

  Baseline, 16 week post-treatment, six month follow-up, every two weeks

• Experiential Avoidance Rating Scale

  Baseline, 16 week post-treatment, six month follow-up

Study Arms (2)

ACT-for-chemsex

EXPERIMENTAL

16 weeks of ACT to reduce chemsex

Behavioral: ACT-for-chemsex

Treatment as usual

ACTIVE COMPARATOR

Treatment as usual

Other: Treatment as Usual (TAU)

Interventions

ACT-for-chemsex BEHAVIORAL

16 weeks of acceptance and commitment therapy, delivered online weekly, 45-55 minute sessions

ACT-for-chemsex

Treatment as Usual (TAU) OTHER

Participants in TAU will receive health/mental health interventions as needed

Treatment as usual

Eligibility Criteria

• Age: 18 Years - 65 Years
• Gender Eligibility Details: Male (as assigned at birth)
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Male
• age 18-65
• access to internet capable smart device
• documentation of Alabama residence
• access to a private area to attend tele ACT-for-chemsex sessions
• self-reported chemsex within six-months of intake
• English fluency.

You may not qualify if:

• Psychotic disorder
• bipolar disorder
• eating disorder
• major neurocognitive disorder diagnosis
• self-harm or suicide attempt within 12 months of screener
• suicide plan/intention at time of screening
• ongoing treatment for a complex medical comorbidity (e.g., in patient cancer treatment)
• current enrollment in an individual ACT-based psychotherapy intervention.

Sponsors & Collaborators

• University of Alabama at Birmingham: lead

Study Sites (1)

University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States

Location

MeSH Terms

Conditions

Chemsex

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Sexual Behavior; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 21, 2025
• First Posted: May 20, 2025
• Study Start: December 1, 2025
• Primary Completion (Estimated): July 31, 2030
• Study Completion (Estimated): December 31, 2030
• Last Updated: December 15, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will share
• Shared Documents: ANALYTIC CODE
• Time Frame: 1/1/2031 - 1/1/2035
• Access Criteria: Researchers affiliated with Academic institutions.

Locations

US (1)