Effect of Pre-medication With Anti-inflammatory Drugs(Ibuprofen and Dexamethasone)on Post-Endodontic Pain
1 other identifier
interventional
130
1 country
1
Brief Summary
Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain with symptomatic irreversible pulpitis
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_2
Started Feb 2025
Shorter than P25 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 15, 2025
CompletedStudy Start
First participant enrolled
February 15, 2025
CompletedFirst Posted
Study publicly available on registry
May 20, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 15, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 15, 2025
CompletedMay 20, 2025
February 1, 2025
4 months
February 15, 2025
May 17, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
effect of pre-medication(ibuprofen and dexamethasone ) on post-endodontic pain
Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain on visual analogue scale
24 hours
effect of pre-medication(ibuprofen and dexamethasone ) on post-endodontic pain
Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain on visual analogue scale
48 hours
effect of pre-medication(ibuprofen and dexamethasone ) on post-endodontic pain
Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain on visual analogue scale
72 hours
Study Arms (2)
Pain with ibuprofen
ACTIVE COMPARATOREffect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain
Pain with dexamethasone
ACTIVE COMPARATOREffect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain
Interventions
Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain
Effect of pre-medication with anti-inflammatory drugs(ibuprofen and dexamethasone)on Post-Endodontic pain
Eligibility Criteria
You may qualify if:
- Permanent teeth with acutely inflamed pulp without swelling or draining sinus.
- Patients of either gender aged between 18-50 years old.
- Systemically healthy patients.
- Patients who agree to attend for recall appointments and provide a written consent.
You may not qualify if:
- Patients on preoperative analgesics and antibiotics.
- Teeth with calcified canals and previously treated teeth.
- Pregnant and lactating mothers.
- Patients who are immunocompromised, anxious and mentally handicapped.
- Patients who are allergic to any of the test medications.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Armed Forces Institute Of Dentistry
Rawalpindi, 46000, Pakistan
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Quratulain Abbasi, BDS
AFID
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Post-Graduate Resident Operative Dentistry & Endodontic
Study Record Dates
First Submitted
February 15, 2025
First Posted
May 20, 2025
Study Start
February 15, 2025
Primary Completion
June 15, 2025
Study Completion
June 15, 2025
Last Updated
May 20, 2025
Record last verified: 2025-02