NCT06980467

Brief Summary

This study examines how artificial intelligence systems interact with medical professionals. Researchers will compare physician responses to different AI-generated outputs in simulative medical scenarios.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
8

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2025

Geographic Reach
1 country

2 active sites

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2025

Completed
17 days until next milestone

Study Start

First participant enrolled

May 15, 2025

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 20, 2025

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 22, 2025

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 23, 2025

Completed
Last Updated

May 20, 2025

Status Verified

May 1, 2025

Enrollment Period

7 days

First QC Date

April 28, 2025

Last Update Submit

May 12, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Physician Response to AI-Generated Medical Content

    Participants will rate their level of agreement with AI-generated clinical suggestions presented in simulated medical scenarios. Responses will be recorded using a standardized rating scale (range 1-5, where higher scores indicate better agreement).

    Through study completion, an average of 1 week

Secondary Outcomes (1)

  • Physician Perception of Communication Quality in AI-Generated Content

    Through study completion, an average of 1 week

Study Arms (2)

control group

NO INTERVENTION

Participants evaluate clinical recommendations generated by Language Model A (LLM-A), with subsequent assessments of communication style characteristics using rating scales.

intervention group

EXPERIMENTAL

Participants evaluate clinical recommendations generated by Language Model B (LLM-B), followed by evaluations of communication style characteristics through metric instruments.

Other: Large Language Model

Interventions

An artificial intelligence system generating clinical recommendations using prompts, designed to simulate clinical advisory outputs. The protocol focuses on structured medical language generation.

intervention group

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 18 years old;
  • Licensed physician or medical professional qualified to perform clinical evaluations;
  • Willing to sign informed consent and commit time to participate in the study.

You may not qualify if:

  • Unable to dedicate sufficient time to complete the study tasks;
  • Unable or unwilling to understand and follow study instructions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Tsinghua University

Beijing, Beijing Municipality, 100084, China

Location

Shanghai Health and Medical Center

Wuxi, Jiangsu, 214065, China

Location

MeSH Terms

Interventions

Large Language Models

Intervention Hierarchy (Ancestors)

Deep LearningMachine LearningArtificial IntelligenceAlgorithmsMathematical ConceptsNeural Networks, Computer

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Vice-Provost and Senior Vice-Chancellor

Study Record Dates

First Submitted

April 28, 2025

First Posted

May 20, 2025

Study Start

May 15, 2025

Primary Completion

May 22, 2025

Study Completion

May 23, 2025

Last Updated

May 20, 2025

Record last verified: 2025-05

Locations