NCT06977503

Brief Summary

This clinical trial evaluates the effect of life coaching together with Cranial Electrotherapy Stimulation (CES) as an intervention to decrease self-reported symptoms of burnout, moral distress, resilience, and employee retention in oncology healthcare workers. Burnout and moral distress are occupational hazards for oncology healthcare workers. Emotional exhaustion, depersonalization, and lack of personal accomplishment at work are symptoms of burnout. Moral distress may be defined as knowing the right thing to do but being unable to do so based upon internal or external constraints. The device is attached to the earlobes that uses cranial electrotherapy stimulation (CES) at a microcurrent to alleviate symptoms of anxiety, insomnia, pain, and possibly depression. Life coaching is partnering with clients in a thought-provoking and creative process that inspires them to maximize their personal and professional potential and can increase resiliency skills such as boundary setting and prioritizing, increases in self-compassion and self-care, and potentially indirectly positively impact patient care. Undergoing the use of CES via the CES device, coupled with life coaching, may help alleviate burnout symptoms and moral distress in oncology healthcare workers.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
15mo left

Started Aug 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 9, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 18, 2025

Completed
1.2 years until next milestone

Study Start

First participant enrolled

August 1, 2026

Expected
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2026

1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

October 15, 2027

Last Updated

June 9, 2026

Status Verified

June 1, 2026

Enrollment Period

3 months

First QC Date

May 9, 2025

Last Update Submit

June 8, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Symptoms of burnout in healthcare workers (HCWs)

    Will be assessed using the Mini-Z Survey. Will be summarized by study arm and time-point (baseline, midpoint, and follow-up) using the appropriate descriptive statistics, and graphically using mean or dot plots. The Mini-Z scores will be modeled as a function of study arm, time-point, their two-way interaction, and random cohort and subject (nested within cohort) effects using linear mixed models (LMMs).

    At baseline, 6 weeks, and 13 weeks

  • Symptoms of moral distress in HCWs

    Will be assessed using the Measure of Moral Distress for Healthcare Workers (MMDHW). Will be summarized by study arm and time-point (baseline, midpoint, and follow-up) using the appropriate descriptive statistics, and graphically using mean or dot plots. The MMDHW scores will be modeled as a function of study arm, time-point, their two-way interaction, and random cohort and subject (nested within cohort) effects using LMMs.

    At baseline, 6 weeks, and 13 weeks

Secondary Outcomes (2)

  • Self-reported resilience in HCWs

    At baseline, 6 weeks, and 13 weeks

  • HCW self-reported probability of employment retention

    At baseline, 6 weeks, and 13 weeks

Study Arms (2)

Arm I (Cranial Electrotherapy Stimulation (CES) + life coaching)

EXPERIMENTAL

During weeks 1-6, participants use the CES device QD over 1 hour 5 days per week for 6 weeks on study. Participants also participate in virtual group life coaching sessions and discussions and view video assignments 3 times during weeks 1, 3, and 6. At week 7 participants will return their devices and receive their second device . During weeks 8-13 participants cross-over and use the sham device QD over 1 hour 5 days per week for 6 weeks on study.

Other: DiscussionBehavioral: Health and Wellness CoachOther: Informational InterventionOther: Survey Administration

Arm II (Sham device + life coaching sessions)

SHAM COMPARATOR

During weeks 1-6, participants use the sham device QD over 1 hour 5 days per week for 6 weeks on study. Participants also participate in virtual group life coaching sessions and discussions and view video assignments 3 times during weeks 1, 3, and 6. At week 7, participants return their device and receive their second device. During weeks 8-13, participants cross-over and use the CES device QD over 1 hour 5 days per week for 6 weeks on study.

Procedure: Cranial Electrical Stimulation (CES)Other: DiscussionBehavioral: Health and Wellness CoachOther: Informational InterventionProcedure: Sham InterventionOther: Survey Administration

Interventions

Use CES device

Arm II (Sham device + life coaching sessions)

Participate in discussions

Also known as: Discuss
Arm I (Cranial Electrotherapy Stimulation (CES) + life coaching)Arm II (Sham device + life coaching sessions)

Undergo coaching sessions

Arm I (Cranial Electrotherapy Stimulation (CES) + life coaching)Arm II (Sham device + life coaching sessions)

View video assignments

Arm I (Cranial Electrotherapy Stimulation (CES) + life coaching)Arm II (Sham device + life coaching sessions)

Undergo sham intervention

Also known as: Sham Comparator
Arm II (Sham device + life coaching sessions)

Ancillary studies

Arm I (Cranial Electrotherapy Stimulation (CES) + life coaching)Arm II (Sham device + life coaching sessions)

Eligibility Criteria

Age21 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 21 ≤ and ≤ 75 years old
  • Patient-facing healthcare workers (e.g., medical doctor, advanced practice provider, nurse)
  • Experiencing symptoms of burnout, as defined by a score of 1, 2, or 3 on question #2 of the Mini-Z II Survey
  • Working on the Buffalo-Niagara Medical Campus (e.g. Roswell Park, Oishei Children's Hospital, Buffalo General, etc.)
  • Ability to attend three (3) in-person appointments, one (1) hour in duration, at Roswell Park at week 1, week 6 and week 12 corresponding to the initial, midpoint, and final assessments
  • Ability to use the CES daily for an hour each day
  • Although the device is water-resistant, participants must agree to not use the device in the bath or shower
  • Ability to read and write in English
  • Participant has access to a computer with internet access and an email address
  • Ability to attend three (3) virtual 60-minute group life coaching sessions, via Zoom
  • Ability to complete three (3) 10-15-minute pre-recorded video assignments, which will be distributed via email (each assignment will be due by the end of the week that they are distributed)
  • Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure

You may not qualify if:

  • Subjects who self-report as pregnant or nursing. Pregnancy be verified with a urine test for all persons of childbearing potential with a uterus
  • Subjects with a self-reported history of the following: Meniere's disease, history of vertigo or prone to dizziness, seizure disorder, pacemaker / implantable cardioverter-defibrillator (automatic implantable cardioverter defibrillator \[AICD\]), cochlear implant, or any implanted electrical devices that cannot be shut off
  • Inability to tolerate the required minimum stimulation amplitude (200 uA) during the initial device training at the baseline visit.
  • Any self-reported medical or psychiatric condition which in the PI or study physician's opinion deems the participant an unsuitable candidate to participate in this trial.
  • Unwilling or unable to follow protocol requirements

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Roswell Park Cancer Institute

Buffalo, New York, 14263, United States

RECRUITING

MeSH Terms

Conditions

Mental Disorders

Interventions

Health

Intervention Hierarchy (Ancestors)

Population Characteristics

Study Officials

  • Amy Gallagher, PsyD

    Roswell Park Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Masking Details
Researchers will be blinded with respect to subjects' study number, pre/post assessment data, and CES group (e.g., Group A versus Group B), the participants will remain blinded to which device they received (either sham or investigational device) throughout the duration of the study.
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 9, 2025

First Posted

May 18, 2025

Study Start (Estimated)

August 1, 2026

Primary Completion (Estimated)

October 15, 2026

Study Completion (Estimated)

October 15, 2027

Last Updated

June 9, 2026

Record last verified: 2026-06

Locations