NCT06976528

Brief Summary

Emerging Adults (EA) engage in heavy episodic drinking (HED) at a greater quantity and frequency than any other time in their lives, which may lead to significant short- and long-term consequences. Although much is known about the influence of peers in EA alcohol use, there is a dearth of research examining the ways in which romantic partners influence EA drinking behaviors. The proposed study bridges a crucial gap in the existing literature by examining behavioral and physiological risk and resilience factors in the acute link between EA relationship conflict and alcohol consumption. EA couples will engage in two conflict resolution tasks interspersed with two puzzle tasks and two alcohol administration procedures. Because high frequency heart rate variability (HF-HRV) is associated with alcohol use and emotion regulation during stressful experiences, HF-HRV and other physiological data will be collected throughout the laboratory procedures.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P50-P75 for all trials

Timeline
28mo left

Started Sep 2025

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress22%
Sep 2025Jul 2028

First Submitted

Initial submission to the registry

May 8, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 16, 2025

Completed
4 months until next milestone

Study Start

First participant enrolled

September 26, 2025

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2028

Last Updated

February 20, 2026

Status Verified

September 1, 2025

Enrollment Period

2.8 years

First QC Date

May 8, 2025

Last Update Submit

February 18, 2026

Conditions

Keywords

couplesemerging adultsyoung adultsbinge drinkingalcohol useconflict

Outcome Measures

Primary Outcomes (1)

  • Alcohol consumption

    Amount of alcohol consumed during the study

    ~20 minutes

Secondary Outcomes (1)

  • High frequency heart rate variability (HF-HRV)

    ~3 hours

Eligibility Criteria

Age21 Years - 29 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Emerging adults in couples in the NYC area

You may qualify if:

  • Age 21-29 years old
  • Must be in a committed romantic relationship of at least 3 months duration
  • Must report at least 2 HED episodes in the past 30 days (5 or more drinks within 2 hours for males, 4 or more drinks within 2 hours for females)
  • Must self-report that they have - on at least three occasions during the past year - consumed a quantity of alcohol that is equal to or greater than the standard dose administered for their weight in the laboratory

You may not qualify if:

  • Meeting DSM-5 criteria for a history of or current neurological, psychotic, or bipolar disorders
  • History of self-reported head trauma requiring medical treatment
  • Body weight exceeding 250 pounds
  • Current enrollment in treatment or seeking treatment for a substance or alcohol use disorder
  • Current suicidal or homicidal intent
  • Serious cardiovascular health conditions (e.g. pacemaker, cardiac arrhythmia, hypertension) that may alter normative cardiac functioning
  • Treatment on medications such as lithium, methadone, alpha or beta blockers or cholinergic/anticholinergic medications likely to confound normative cardiovascular responding or response to alcohol administration. Stimulant or benzodiazepine medication use is permissible provided participants do not take medication on the day of study participation
  • Severe and/or unilateral physical IPV with your current partner at any time
  • Sexual IPV with current partner at any time
  • Fear of current partner
  • Pregnancy or breastfeeding
  • Severe Alcohol Use Disorder (as defined by the DSM-5)
  • Current diagnosis of anorexia or bulimia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

386 Park Avenue South

New York, New York, 10016, United States

RECRUITING

MeSH Terms

Conditions

Binge DrinkingAlcohol Drinking

Condition Hierarchy (Ancestors)

Alcohol-Related DisordersSubstance-Related DisordersChemically-Induced DisordersDrinking BehaviorBehaviorMental Disorders

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 8, 2025

First Posted

May 16, 2025

Study Start

September 26, 2025

Primary Completion (Estimated)

July 31, 2028

Study Completion (Estimated)

July 31, 2028

Last Updated

February 20, 2026

Record last verified: 2025-09

Locations