Comparison of a Face Cream Plus a Laser Procedure and Face Cream Alone in Treatment of Excessive Face Hairs in Female

NCT06976424 | Recruiting Phase 4

• 1 other identifier: 59/DME/KMC
• Study Type: interventional
• Target: 122
• Locations: 1 country
• Sites: 3

Brief Summary

The study compares the effects of a cream alone and a combined effect of cream and laser for the treatment of excessive facial hairs in women .

Conditions

Hirsuitism

Keywords

Hirsuitism; IPL; Eflornithine

Outcome Measures

Primary Outcomes (1)

• Efficacy of treatment

  Efficacy of treatment is defined as complete clearance of excessive hairs assesed on the basis of 4- level scale ranging 0 to 3 after 3 months of administration of the treatment in both groups. Clear is grade 3 Marked improvement is grade2 Improved is grade1 No improvement is grade 0

  3 months

Study Arms (2)

GroupA

EXPERIMENTAL

This group is treated with combination of eflornithine cream and intense pulsed light for a period of three month.

Radiation: Instense pulsed light; Drug: Eflornithine Topical

Group B

EXPERIMENTAL

This group is treated with eflornithine cream twice daily only for a period of three month

Drug: Eflornithine Topical

Interventions

Eflornithine Topical DRUG

Eflornithine cream will be applied to the face of group B female patients

Also known as: Eflornithine cream

Group B

Instense pulsed light RADIATION

Intense pulse light will be applied to the face of patient of Group A on areas having increase hair. Patient will be called for a followup every month for next session.

GroupA

Eligibility Criteria

• Age: 18 Years - 45 Years
• Gender Eligibility Details: All the female patients with excessive facial hairs were included in the study.
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Gender (Female) Age between 18-45 Years Women with hirsutism as mentioned in the operational definition

You may not qualify if:

• Pregnant women Women with severe acne Women with immunodeficiency

Sponsors & Collaborators

• Khyber Teaching Hospital: lead

Study Sites (3)

Khyber Teaching Hospital

Peshawar, Kpk, 25000, Pakistan

RECRUITING

Khyber Teaching Hospital

Peshawar, KPK, Pakistan

RECRUITING

Khyber Teachinng Hospital

Peshawar, KPK, Pakistan

RECRUITING

MeSH Terms

Conditions

Hirsutism

Interventions

Eflornithine

Condition Hierarchy (Ancestors)

Hair Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Virilism; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Ornithine; Amino Acids, Basic; Amino Acids; Amino Acids, Peptides, and Proteins; Amino Acids, Diamino

Central Study Contacts

Umaima Nazar, MBBS

CONTACT

+923355869079; umaimanazar123@gmail.com

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: May 9, 2025
• First Posted: May 16, 2025
• Study Start: July 15, 2025
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: July 3, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (3)