NCT06971263

Brief Summary

Cancer patients are more likely to have malnutrition, which has been associated with poorer quality of life, higher morbidity, mortality rates, and impaired efficacy and tolerance to therapy. Malnutrition is thought to afflict the cancer patients, with weight loss and varied degrees of asthenia being the main symptoms. In fact, malnutrition can increase the risk of surgical complications such as anastomosis dehiscence, poor wound healing, morbidity, and mortality. Quality of Life is among the most important health issues for cancer patients. Patients view it as a specific and complex type of patient-reported outcomes (PROs) that considers their social, economic, psychological, and physical activities. The quality of life for cancer patients is often lower than for the general population. Despite the fact that several studies in the Western population have suggested a relationship between nutritional status and quality of life (QoL). There aren't many reliable, in-depth studies on the effectiveness of nutritional testing and early malnutrition therapy, as well as to look at the nutritional health and quality of life of cancer patients in Bangladesh. Therefore, the aim of this study is to outline the Influence of Dietary and Palliative Care Consultation on the Quality of Life (Qol), Performance Status, and Nutritional Status of Cancer Patients in Bangladesh. To conduct this randomized control trial (RCT), data will be collected through 3 observations: baseline survey with two follow-up surveys on the following months from the selected cohorts of cancer patients who will be receiving cancer treatments. There will be two groups of cohort, one will be given nutrition and palliative care counselling will be given as intervention during each observation and another group will be without consultancy. "The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire version 3.0 (EORTC-QLQ C30)", "The Patient-Generated Subjective Global Assessment PG-SGA)" to estimate nutritional status, and "The Eastern Cooperative Oncology Group's (ECOG) scale" to determine the performance status (PS) will be used as instruments to collect data.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
215

participants targeted

Target at P75+ for not_applicable cancer

Timeline
3mo left

Started Jun 2025

Geographic Reach
1 country

3 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
Jun 2025Sep 2026

First Submitted

Initial submission to the registry

April 17, 2025

Completed
27 days until next milestone

First Posted

Study publicly available on registry

May 14, 2025

Completed
1 month until next milestone

Study Start

First participant enrolled

June 15, 2025

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2026

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Expected
Last Updated

September 2, 2025

Status Verified

August 1, 2025

Enrollment Period

10 months

First QC Date

April 17, 2025

Last Update Submit

August 25, 2025

Conditions

Keywords

CancerDietary ConsultationPalliative CareQuality of LifePerformance StatusNutritional Status

Outcome Measures

Primary Outcomes (1)

  • Patient-Generated Subjective Global Assessment (PG-SGA) Scale

    The Patient-Generated Subjective Global Assessment (PG-SGA) instrument will be used to diagnose nutrition. The technique permits categorizing the nutritional evaluation into three groups: A for well-nourished, B for suspected or moderate malnutrition, and C for severe malnutrition. Weight in kilograms divided by height in squared meter is known as the body mass index (BMI). In addition to PG-SGA, BMI will be calculated and categorized according to the age-specific and sex-specific chart created by the US Centers for Disease Control and Prevention.

    From enrollment to the end of interventions at 10 weeks.

Secondary Outcomes (1)

  • Eastern Cooperative Oncology Group's (ECOG) scale

    From enrollment to the end of interventions at 10 weeks.

Other Outcomes (1)

  • European Organization for Research and Treatment of Cancer Quality of Life Questionnaire version 3.0 (EORTC-QLQ-C30) scale

    From enrollment to the end of interventions at 10 weeks.

Study Arms (3)

Cancer patients with both face-to face nutrition and palliative care counselling

ACTIVE COMPARATOR

Recruited cancer patients will be given both nutrition and palliative care counselling during face-to face surveys.

Behavioral: Consultation on both nutrition, and palliative care

Cancer patients with face-to face nutrition counselling

ACTIVE COMPARATOR

Recruited cancer patients will be given nutrition counselling on healthy diet during face-to face surveys.

Behavioral: Counselling on nutrition and healthy diet

Cancer patients without any consultation or intervention

NO INTERVENTION

Recruited cancer patients will not be given any nutrition and palliative care counselling or interventions during face-to face surveys.

Interventions

The intervention on the nutrition and palliative care components will include open-ended consultations based on ESPEN practical guidelines on nutrition in cancer patients with one cancer center dietitian and one palliative care physician to discuss patient needs and required to improve their health consequences.

Cancer patients with both face-to face nutrition and palliative care counselling

The intervention on the nutrition and healthy diet components will include open-ended consultations based on ESPEN practical guidelines on nutrition in cancer patients with one cancer center dietitian to discuss patient dietary needs for improving their health consequences.

Cancer patients with face-to face nutrition counselling

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Cancer Patients under standard treatment, Willing to participate, Who can eat orally, and Health indicators are measurable.

You may not qualify if:

  • Cancer Patients under no standard treatment, Not willing to participate, Who cannot eat orally, Health indicators are not measurable, and Death.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Chittagong Medical College Hospital (CMCH)

Chittagong, Chattogram, 4203, Bangladesh

RECRUITING

Department of Public Health and Informatics, Jahangirnagar University

Savar Upazila, Dhaka Division, 1342, Bangladesh

ACTIVE NOT RECRUITING

Mymensingh Medical College Hospital (MMCH)

Mymensingh, Mymensingh, 2200, Bangladesh

RECRUITING

Related Links

MeSH Terms

Conditions

Neoplasms

Interventions

Palliative CareDiet, Healthy

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and ServicesDietNutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena

Study Officials

  • Syed Billal Hossain, MPH

    Jahangirnagar University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Syed Billal Hossain, MPH

CONTACT

Mahfuza Mubarak, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Masking Details
Data collectors
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Randomized Control Trial (RCT)
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD Student

Study Record Dates

First Submitted

April 17, 2025

First Posted

May 14, 2025

Study Start

June 15, 2025

Primary Completion

April 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

September 2, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share

IPD related to the cancer patients with intervention might be shared on reasonable requests related to research, review and citation.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
April 2026 to March 2028
Access Criteria
Access to IPD will be given on reasonable requests related to research, review and citation.

Locations