NCT06969911

Brief Summary

The aim of the study is to clinically evaluate tooth-supported veneer restorations fabricated using the CAD/CAM process in comparison to conventionally manufactured pressed veneers on anterior teeth and to assess their long-term performance. Survival and success rates of anterior veneer restorations, as well as patient satisfaction, will be evaluated.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
72mo left

Started May 2025

Longer than P75 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress15%
May 2025Mar 2032

Study Start

First participant enrolled

May 5, 2025

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

May 6, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

May 14, 2025

Completed
6.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2032

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2032

Last Updated

May 14, 2025

Status Verified

January 1, 2025

Enrollment Period

6.9 years

First QC Date

May 6, 2025

Last Update Submit

May 6, 2025

Conditions

Malformed Tooth

Outcome Measures

Primary Outcomes (1)

  • Prosthetic survival time

    The primary objective is to compare the prosthetic survival time of the restorations (conventional vs. CAD/CAM veneers).

    5 Years

Secondary Outcomes (1)

  • Prosthetic success

    5 Years

Study Arms (2)

Control Group: Conventional veneer restoration

SHAM COMPARATOR

Therapeutic intervention with minimally invasive traditionally fabricated all-ceramic anterior veneers.

Procedure: Laminate Veneer Convetional

Study Group: CAD/CAM veneer restoration

ACTIVE COMPARATOR

Therapeutic intervention with minimally invasive CAD/CAM all-ceramic anterior veneers.

Procedure: Laminate veneer CAD/CAM

Interventions

Laminate veneer CAD/CAMPROCEDURE

Minimally invasive therapeutic intervention with CAD/CAM veneers

Study Group: CAD/CAM veneer restoration
Laminate Veneer ConvetionalPROCEDURE

Minimally invasive therapeutic intervention with CAD/CAM veneers

Control Group: Conventional veneer restoration

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients ≥ 18 years of age
  • Patients that reveal indication for a minimum of 2 and a maximum of 6 anterior veneer restorations

You may not qualify if:

  • \- Patients that reveal multiple missing teeth, poor oral hygiene, pronounced parafunctions or with allergies to any of the applied materials

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Tooth Abnormalities

Condition Hierarchy (Ancestors)

Stomatognathic System AbnormalitiesStomatognathic DiseasesTooth DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 6, 2025

First Posted

May 14, 2025

Study Start

May 5, 2025

Primary Completion (Estimated)

March 31, 2032

Study Completion (Estimated)

March 31, 2032

Last Updated

May 14, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will not share