Nerve Block Treatment for Chronic Jaw Pain

NCT06966557 | Recruiting

• 1 other identifier: BnaiZion -TMJ2025
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Study Summary: Nerve Block Treatment for Chronic Jaw Pain This study is being conducted at the TMJ (temporomandibular joint) clinic, which is part of the oral and maxillofacial surgery department. The goal is to evaluate how effective peripheral nerve blocks are in reducing long-term jaw pain in patients with chronic temporomandibular disorders (TMD) who haven't responded to at least two other types of treatment (such as physical therapy, medication, or bite splints). What Is the Treatment? Peripheral nerve blocks are injections that temporarily block nerve signals from the painful area. This can relieve pain and improve function. These blocks are already used routinely at the clinic. Who Can Join? Adults who have had jaw joint pain for over a year. Have tried at least two other treatments without success. Are mentally competent and not pregnant. What Will Participation Involve? You'll receive the nerve block treatment as part of your regular care. You'll be asked to attend follow-up visits, typically one every 4 months (3 per year). You'll be monitored for pain relief, mouth opening ability, and use of pain medications. You can stop participating at any time without affecting your care. How Will Data Be Handled? Your information will be stored securely and coded to protect your identity. Only the research team will have access to your personal information. How Many People Will Be in the Study? The goal is to recruit 40 patients.

Conditions

TMJ Pain

Keywords

TMJ Pain; Nerve block; Peripheral nerve block; Chronic temporomandibular pain

Outcome Measures

Primary Outcomes (1)

• VAS pain intensity

  Pain intensity will be assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst pain imaginable), before and after treatment.

  One year

Secondary Outcomes (2)

• Mouth opening meausurement

  One year

• Change in analgesic use

  One year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients with chronic temporomandibular joint (TMJ) pain who attend the TMJ clinic at Beni Zion hospital, part of the Department of Oral and Maxillofacial Surgery. Participants are individuals who have experienced TMJ-related pain for at least one year and have not responded adequately to at least two prior treatment modalities (e.g., physiotherapy, medications, splints, or alternative therapies). Eligible patients will be those for whom a peripheral nerve block has been selected as part of their clinical care.

You may qualify if:

• Adults (non-pregnant) with sound judgment
• Chronic TMJ pain lasting at least 12 months
• Documented failure of at least two previous treatment modalities

You may not qualify if:

• Missing at least two follow-up visits within the specified timeframe

Sponsors & Collaborators

• Bnai Zion Medical Center: lead

Study Sites (1)

Department of Oral and Maxillofacial Surgery

Haifa, North, 3199500, Israel

RECRUITING

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 4, 2025
• First Posted: May 12, 2025
• Study Start: April 25, 2025
• Primary Completion: May 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: June 10, 2025

Record last verified: 2025-04

Locations

IL (1)