NCT06965530

Brief Summary

Medically tailored groceries (MTG), involving grocery items to be prepared at home, selected by a nutritional professional based on a treatment plan, is a growing approach adopted by healthcare systems to address food insecurity in their patient populations, a leading contribution to health disparities such as poor birth outcomes within pregnant populations. However, transportation and other social needs can often hinder patient uptake of clinic-based approaches. Findings from this study will help to better understand how home delivery of MTGs, with and without supplemental education and support to improve food literacy, behavioral and health outcomes.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
360

participants targeted

Target at P75+ for not_applicable

Timeline
37mo left

Started Nov 2025

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress14%
Nov 2025May 2029

First Submitted

Initial submission to the registry

April 11, 2025

Completed
1 month until next milestone

First Posted

Study publicly available on registry

May 11, 2025

Completed
6 months until next milestone

Study Start

First participant enrolled

November 12, 2025

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2028

Expected
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2029

Last Updated

April 20, 2026

Status Verified

April 1, 2026

Enrollment Period

3 years

First QC Date

April 11, 2025

Last Update Submit

April 16, 2026

Conditions

Keywords

Randomized trialBehavioral intervention

Outcome Measures

Primary Outcomes (6)

  • Food Insecurity

    6 item, United States Department of Agriculture (USDA) measure; dichotomous outcome

    Change from baseline to delivery (assessed up to 40 weeks of pregnancy)

  • Food Insecurity

    6 item, USDA measure; dichotomous outcome

    Change from baseline to 6-months post delivery

  • Baby Gestational Age

    Measured in weeks and classified as preterm (\<37 weeks) vs. term (37+ weeks)

    At birth

  • Baby Birthweight

    Measured in grams and classified as normal (\> or = 2500g), low birth weight (\<2500g), very low birthweight (\<1500g), extremely low birth weight (\<1000g)

    At birth

  • Days Hospitalized (Baby)

    Number of days baby was hospitalized following birth

    From date of birth until the date of discharge from the hospital, assessed up to 100 months

  • Neonatal Intensive Care Unit (NICU)/Special Care Nursery (SCN) Utilization

    Number of days baby was admitted to NICU or SCN

    From admission date to the NICU/SCN until the date of discharge from NICU/SCN, assessed up to 100 months

Secondary Outcomes (24)

  • Birth Complications

    Perioperative/periprocedural

  • Prenatal Health Care

    From first documented prenatal visit until the baby's delivery date, assessed up to 9 months

  • Pregnancy Complications

    Perioperative/periprocedural

  • Gestational Diabetes Mellitus (GDM)

    Assessed up to 40 weeks of pregnancy

  • Attitudes toward Cooking and Food Preparation

    Change from baseline to delivery (assessed up to 40 weeks of pregnancy)

  • +19 more secondary outcomes

Study Arms (3)

Clinic-Based Medically Tailored Groceries (CB-MTG)

ACTIVE COMPARATOR

Standard of Care: Patients enrolled in the health systems clinic-based Food is Medicine Program.

Dietary Supplement: Clinic-Based Medically Tailored Groceries (CB-MTG)

Home Delivered Medically Tailored Groceries (HD-MTG)

EXPERIMENTAL

Patient received home delivered medically tailored groceries every two weeks during pregnancy and up to 3 months post-delivery.

Dietary Supplement: Home Delivered Medically Tailored Groceries (HD-MTG)

Home Delivered Medically Tailored Groceries PLUS (HD-MTGPLUS)

EXPERIMENTAL

Same as Arm 2, receiving home delivered medically tailored groceries every two weeks during pregnancy and up to 3 months post-delivery, but receives additional nutrition and culinary education and support throughout the trial.

Dietary Supplement: Home Delivered Medically Tailored Groceries plus Education (HD-MTG_PLUS)

Interventions

Patients have the opportunity to pick up medically tailored groceries every other week at the Food Is Medicine Clinic or Market associated with their provider.

Clinic-Based Medically Tailored Groceries (CB-MTG)

Patient receive home delivered medically tailored groceries every two weeks during pregnancy and up to 3 months post-delivery.

Home Delivered Medically Tailored Groceries (HD-MTG)

Patients receive home delivered medically tailored groceries every two weeks during pregnancy and up to 3 months post-delivery, plus also receives additional nutrition and culinary education and support throughout the trial.

Home Delivered Medically Tailored Groceries PLUS (HD-MTGPLUS)

Eligibility Criteria

Age18 Years - 55 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • years of age and older
  • Pregnant patients \>10 weeks and \<22 weeks gestation at randomization (must be consented by 18 weeks)
  • Eligible for Medicaid
  • Singleton pregnancy, confirmed by ultrasound
  • An established patient of the UH or Metro pregnancy clinic
  • English speaking
  • Lives in Cuyahoga County, Ohio

You may not qualify if:

  • Under 18 years old

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

MetroHealth Medical Center

Cleveland, Ohio, 44106, United States

RECRUITING

University Hospitals Rainbow Ahuja Women and Children's Center

Cleveland, Ohio, 44106, United States

RECRUITING

MeSH Terms

Conditions

Premature BirthPregnancy Complications

Interventions

Educational Status

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation Characteristics

Study Officials

  • Elaine A Borawski, PhD

    Case Western Reserve University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Samantha Bentley, MPH

CONTACT

Elaine A Borawski, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Vice Chair for Applied Research, Department of Nutrition

Study Record Dates

First Submitted

April 11, 2025

First Posted

May 11, 2025

Study Start

November 12, 2025

Primary Completion (Estimated)

November 1, 2028

Study Completion (Estimated)

May 31, 2029

Last Updated

April 20, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will share

As required by our National Institute of Nursing Research grant award, please see the required Data Management and Sharing Plan (uploaded as separate document). In brief, at the of the study, de-identified questionnaire, clinical and implementation data will be deposited into the Inter-university Consortium for Political and Social Research (ICPSR) and designated as controlled access. Case Western Reserve University (CWRU) is a member of ICPSR which permits the deposit of data at no charge.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR
Time Frame
Within 6 months of the primary outcomes paper being published.

Locations