NCT06960733

Brief Summary

This study was randomized, controlled, blinded trial with a two-arm parallel-group design to directly compare the therapeutic outcomes of winged versus conventional stents in patients with benign or malignant biliopancreatic conditions requiring ERCP and subsequent insertion or replacement of plastic stents.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2011

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2013

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2013

Completed
11.3 years until next milestone

First Submitted

Initial submission to the registry

April 28, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 7, 2025

Completed
Last Updated

May 7, 2025

Status Verified

October 1, 2010

Enrollment Period

1.9 years

First QC Date

April 28, 2025

Last Update Submit

April 28, 2025

Conditions

Keywords

ERCPBiliary obstructionbiliary stentingplastic stent

Outcome Measures

Primary Outcomes (1)

  • Dysfunction

    Sign of dysfunction of biliary stenting (fever, pain, jaundice)

    3 Months

Study Arms (2)

Conventional Stenting

ACTIVE COMPARATOR

Stenting of biliary tract by standard plastic stent. Change of stent-type at regular stent exchange after three months (from winged to standard and vice versae).

Device: Winged plastic stentDevice: Standard plastic stents

Winged Stent

EXPERIMENTAL

Stenting of biliary tract by use of winged-design stent. Change of stent-type at regular stent exchange after three months (from winged to standard and vice versae).

Device: Winged plastic stentDevice: Standard plastic stents

Interventions

Patient with need for stenting of bile duct were randomised for kind of stents. Stents used were either standard plastic stents or stents with winged design. In this Intervention winged stents were used.

Conventional StentingWinged Stent

Patient with need for stenting of bile duct were randomised for kind of stents. Stents used were either standard plastic stents or stents with winged design. In this Intervention standard plastic stents were used.

Conventional StentingWinged Stent

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Biliopancreatic disorder requiring plaxtic biliary stent therapy
  • written informed consent

You may not qualify if:

  • Pregnancy
  • Breastfeeding
  • Live Expectancy of less than one month
  • Biliary drainage by metal stent or external drainage.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Leipzig Medical Center, Department of Gastroenterology

Leipzig, Saxony, 04103, Germany

Location

MeSH Terms

Conditions

CholecystolithiasisBiliary Tract Neoplasms

Condition Hierarchy (Ancestors)

CholelithiasisBiliary Tract DiseasesDigestive System DiseasesGallbladder DiseasesDigestive System NeoplasmsNeoplasms by SiteNeoplasms

Study Officials

  • Albrecht Hoffmeister, Professor

    University of Leipzig Medical Center

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2025

First Posted

May 7, 2025

Study Start

June 1, 2011

Primary Completion

April 30, 2013

Study Completion

December 31, 2013

Last Updated

May 7, 2025

Record last verified: 2010-10

Data Sharing

IPD Sharing
Will not share

Locations