Dosage of Early Rehabilitation of ICU Patients

NCT06960642 | Recruiting

• 1 other identifier: ERUPT
• Study Type: observational
• Target: 6,000
• Locations: 1 country
• Sites: 1

Brief Summary

Rehabilitation already begins in the intensive care unit (ICU) to maintain or restore the functional capacity of ICU patients and to counteract the long-term effects of intensive care treatment. Mobilisation is an important component. The aim of this multinational observational study is to record and evaluate the different mobilisation practices for ICU patients worldwide. The investigators want to find out which forms of mobilisation in intensive care patients achieve the best results in terms of physical function, functional status and quality of life. The goal is to recruit over 6,000 patients internationally. No interventions will be carried out, only routine clinical data will be documented and standardised and already established physical tests and questionnaires will be used.

Conditions

Critical Care, Intensive Care; Critical Illness; Physiotherapy; Early Ambulation; Interprofessional Team Collaboration

Keywords

early ambulation; early rehabilitation; early mobilisation; physiotherapy; Physical Therapy; ICUAW; PICS; Intensive Care Unit Acquired Weakness; Post Intensive Care Syndrom; Physical Function; Critical Care; Interprofessional; Nursing

Outcome Measures

Primary Outcomes (1)

• Physical function at ICU discharge

  Physical function measured with the Functional Status Score for the Intensive Care Unit (FSS-ICU). The total score ranges from 0 to 35, with higher scores indicating better physical function.

  ICU discharge (up to Day 28)

Secondary Outcomes (10)

• Highest level of mobility at ICU discharge and 90 days

  ICU discharge (up to Day 28) and Day 90

• Physical function at 90 days

  Day 90

• Frailty/ Functional status at ICU discharge and 90 days

  ICU discharge (up to Day 28) and Day 90

• ICU LOS

  ICU admission until ICU discharge (up to Day 28)

• Hospital LOS

  ICU admission until hospital discharge

Study Arms (2)

Independent

Patients who have been functionally independent before ICU admission

Dependent

Patients who have been functionally dependent before ICU admissoin

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Intensive care unit patients

You may qualify if:

• Adults (≥ 18 years old) within 48 hours of ICU admission
• Expected to stay \> 24 hours in the ICU

You may not qualify if:

• Patients who receive end-of-life care at the time of screening
• Patients whose treatment plans are still under discussion and/or not all team members are committed to full active treatment
• Patients whose functional status is unlikely to be obtainable
• Patients with language barriers

Sponsors & Collaborators

• Medical University of Vienna: lead
• European Society of Intensive Care Medicine: collaborator

Study Sites (1)

Medical University of Vienna

Vienna, Vienna, 1090, Austria

RECRUITING

Related Links

• Study Webpage English
• Study Webpage German

MeSH Terms

Conditions

Critical Illness

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Stefan J Schaller, MD

  Medical University of Vienna

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Vera Karner, MSc

CONTACT

+4314040041020; erupt@muv.ac.at

Stefan J Schaller, MD

CONTACT

+4314040041020; aai-research@meduniwien.ac.at

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Anaesthesia and Anaesthesiological Intensive Care Medicine

Study Record Dates

• First Submitted: March 20, 2025
• First Posted: May 7, 2025
• Study Start: December 14, 2025
• Primary Completion (Estimated): March 1, 2027
• Study Completion (Estimated): June 1, 2027
• Last Updated: February 20, 2026

Record last verified: 2026-02

Locations

AU (1)