Predictors of Physical Activity in Adult Patients With Hemophilic Arthropathy

NCT06960499 | Not Yet Recruiting

• 1 other identifier: HeActivity
• Study Type: observational
• Target: 88
• Locations: 1 country
• Sites: 1

Brief Summary

Introduction. The development of hemophilic arthropathy causes degenerative joint damage that leads to functional impairment, limiting physical activity and causing disability in patients with hemophilia. Objectives. i) To assess the level of physical activity in patients with hemophilia; ii) To identify the best predictive model for physical activity in adult patients with hemophilic arthropathy. Material and method. Multicenter cross-sectional cohort study. Eighty-eight patients will be recruited. The dependent variable will be physical activity (International Physical Activity Questionnaire). Secondary variables will be kinesiophobia (Tampa Kinesiophobia Scale), functionality (Functional Independence Scale in Hemophilia), pain intensity, and clinical, anthropometric, and sociodemographic variables.

Conditions

Hemophilia

Keywords

Hemophilia; Physical activity; Kinesiophobia; Functionality; Joint pain

Outcome Measures

Primary Outcomes (1)

• Measurement of physical activity level

  Physical activity levels will be assessed using the International Physical Activity Questionnaire (IPAQ). This tool assesses physical activity levels in adults aged 18 to 65. It consists of seven questions that ask about the frequency, duration, and intensity of physical activity performed in the last week. It also assesses the time spent walking and sitting. The results are classified into three categories: low, moderate, and high activity. The unit of measurement is metabolic equivalent task (METS), where a higher number of METS indicates greater physical activity.

  Screening visit

Secondary Outcomes (12)

• Measurement of fear of movement

  Screening visit

• Measurement of degree of functional independence

  Screening visit

• Measurement of the joint pain

  Screening visit

• Measurement of age

  Screening visit

• Measurement of marital status

  Screening visit

Study Arms (1)

Observacional group

Patients with hemophilia A or B, of legal age, with a medical diagnosis of severe phenotype of the disease and hemophilic arthropathy in the lower limbs.

Other: Surveys

Interventions

Surveys OTHER

No intervention will be carried out in this study; the recruited patients will only complete the questionnaires provided below

Observacional group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with hemophilia A or B and hemophilic arthropathy where it is desired to assess the degree of physical activity and the main predictive factors for this.

You may qualify if:

• Patients with hemophilia A or B
• Over the age of majority
• With a medical diagnosis of severe phenotype of the disease
• With a medical diagnosis of hemophilic arthropathy in the lower limbs
• Under on-demand or prophylactic drug treatment.

You may not qualify if:

• Patients who require technical aids for walking
• Patients who are dependent for activities of daily living
• Patients over the age of 60
• Patients with cognitive impairments that prevent them from understanding the questionnaires

Sponsors & Collaborators

• Universidad Católica San Antonio de Murcia: lead

Study Sites (1)

Universidad Católica San Antonio de Murcia

Murcia, 33006, Spain

Location

MeSH Terms

Conditions

Hemophilia A; Motor Activity; Kinesiophobia; Arthralgia

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Blood Coagulation Disorders, Inherited; Blood Coagulation Disorders; Hematologic Diseases; Hemic and Lymphatic Diseases; Coagulation Protein Disorders; Hemorrhagic Disorders; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Behavior; Phobic Disorders; Anxiety Disorders; Mental Disorders; Joint Diseases; Musculoskeletal Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Rubén Cuesta-Barriuso

  Universidad de Oviedo

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rubén Cuesta-Barriuso, PhD

CONTACT

607547274; cuestaruben@uniovi.es

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 28, 2025
• First Posted: May 7, 2025
• Study Start: May 4, 2025
• Primary Completion: May 28, 2025
• Study Completion: June 20, 2025
• Last Updated: May 7, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)