Postoperative Atrial Fibrillation in Cardiac Surgery

NCT06958029 | Recruiting

• 2 other identifiers: HE671492Khon Kaen University
• Study Type: observational
• Target: 275
• Locations: 1 country
• Sites: 1

Brief Summary

This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in Thailand. The study will examine patient characteristics, surgical factors, and anesthetic management practices that may contribute to the development of this common postoperative complication.

Conditions

Post-operative Atrial Fibrillation

Keywords

postoperative; atrial fibrillation; cardiac surgery

Outcome Measures

Primary Outcomes (1)

• Incidence

  The incidence of POAF

  72 hours postoperatively

Secondary Outcomes (1)

• Risk factors

  72 hours postoperatively

Study Arms (1)

Cardiac surgery

Patients undergoing cardiac surgery

Procedure: Cardiac surgery

Interventions

Cardiac surgery PROCEDURE

Patients receiving general anesthesia for cardiac surgery

Cardiac surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients ubdergoing cardiac surgery

You may qualify if:

• Age ≥ 18 years
• Patients undergoing cardiac valve surgery or coronary artery bypass grafting (CABG) procedures

You may not qualify if:

• Patients undergoing aortic surgery
• Patients undergoing MAZE procedure
• Incomplete medical records
• Patients who required mechanical circulatory support before surgery
• Patients who died during surgery or within 3 days after surgery

Sponsors & Collaborators

• Khon Kaen University: lead

Study Sites (1)

Faculty of Medicine, Khon Kaen University

Khon Kaen, 40002, Thailand

RECRUITING

Related Publications (5)

• Crawford TC, Magruder JT, Grimm JC, Suarez-Pierre A, Sciortino CM, Mandal K, Zehr KJ, Conte JV, Higgins RS, Cameron DE, Whitman GJ. Complications After Cardiac Operations: All Are Not Created Equal. Ann Thorac Surg. 2017 Jan;103(1):32-40. doi: 10.1016/j.athoracsur.2016.10.022. Epub 2016 Nov 22.

  PMID: 27884410 RESULT

• Echahidi N, Pibarot P, O'Hara G, Mathieu P. Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol. 2008 Feb 26;51(8):793-801. doi: 10.1016/j.jacc.2007.10.043.

  PMID: 18294562 RESULT

• Gudbjartsson T, Helgadottir S, Sigurdsson MI, Taha A, Jeppsson A, Christensen TD, Riber LPS. New-onset postoperative atrial fibrillation after heart surgery. Acta Anaesthesiol Scand. 2020 Feb;64(2):145-155. doi: 10.1111/aas.13507. Epub 2019 Dec 2.

  PMID: 31724159 RESULT

• Melduni RM, Koshino Y, Shen WK. Management of arrhythmias in the perioperative setting. Clin Geriatr Med. 2012 Nov;28(4):729-43. doi: 10.1016/j.cger.2012.08.006.

  PMID: 23101581 RESULT

• Lopes LA, Agrawal DK. Post-Operative Atrial Fibrillation: Current Treatments and Etiologies for a Persistent Surgical Complication. J Surg Res (Houst). 2022;5(1):159-172. doi: 10.26502/jsr.10020209. Epub 2022 Mar 28.

  PMID: 35445200 RESULT

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

Cardiac Surgical Procedures

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Thoracic Surgical Procedures

Study Officials

• Thepakorn Sathitkarnmanee, MD

  Khon Kaen University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sirirat Tribuddharat, MD, PhD

CONTACT

66-81-6205921; sirirat.tribuddharat@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: April 27, 2025
• First Posted: May 6, 2025
• Study Start: April 1, 2025
• Primary Completion: June 1, 2025
• Study Completion: June 10, 2025
• Last Updated: May 6, 2025

Record last verified: 2025-04

Locations

TH (1)