Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.

NCT06953856 | Completed

• 1 other identifier: E-71522473-050.01.04-39802-329
• Study Type: interventional
• Target: 140
• Locations: 1 country
• Sites: 1

Brief Summary

Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction. Methods: A total of 140 symptomatic or asymptomatic patients in need of root canal therapy were registered in this prospective, single-center, single-blind, randomized clinical trial. For all patients, root canal treatment was carried out in a single visit, and the teeth were restored using composite resin. The teeth were randomly allocated into two equal groups according to whether occlusal reduction was done or not. The patients' pain were assessed using a 0-3 verbal rate scale 1, 3, and 7 days following root canal treatment. The pain incidence and intensity were compared using the chi-square and Fisher's exact tests.

Conditions

Irriversible Pulpitis

Keywords

Analgesics; Occlusal reduction; Postoperative pain; Single-visit endodontic treatment

Outcome Measures

Primary Outcomes (1)

• Effect of occlusal reduction on pain relief

  This study was primarily aim to understand the effect of occlusal reduction on pain relief after root canal treatment of irriversible pulpitis. After root canal treatment patients were called to estimate their pain levels. A 0-3 rate verbal rating scale was used for this aim. 0: no discomfort or pain 1. mild pain (not requiring analgesic medication) 2. moderate pain (requiring analgesic medication) 3. severe pain (interfering with physical activity and minimally responsive to analgesics)

  from enrollment to the end each patient called for a week to understand their pain levels and each of them called after 1st, 3th, 7th days treatment.

Study Arms (2)

Occlusal reduction,

OTHER

one of the group received occlusal reduction after root canal treatment while other did not.

Other: occlusal reduction

no occlusal reduction

NO INTERVENTION

this group did not receive any occlusal reduction after root canal treatment.

Interventions

occlusal reduction OTHER

Occlusal reduction is a procedure that applied patients for different aims. One of these aims is pain relief after endodontic treatment and there are some studies about this topic however, there is no consensus about it. This discrepency could be related to differences of the inclusion criteria for this reason this study aimed to get a reliable result.

Also known as: occlusal reduction procedure

Occlusal reduction,

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healty patients
• Maxillary and mandibulary first and second molars
• Irriversible pulpitis cases with or without prior discomfort

You may not qualify if:

• Patients under 18 years old,
• Patients older 65 years old,
• Teeth with previously undergone root canal treatment,
• Complicating systemic diseases,
• Allergies o local anesthetic agents,
• Presence of acute apical apsesses,
• History of trauma,
• Analgesic, antibiotic or antiinflamatory intake 7 days before treatment,
• Periodontal pockets deeper than 4 mm,
• Multiple teeth that require endodontic treatment,
• Pregnancy,
• Teeth that can not be restored,
• Patients who needed emergency treatment,
• Grade 2 or 3 mobility,
• Patients with bruxism

Sponsors & Collaborators

• Sakarya University: lead

Study Sites (1)

Sakarya University Facultry of Dentistry

Adapazarı, Sakarya, 54050, Turkey (Türkiye)

Location

Related Publications (6)

• Parirokh M, Rekabi AR, Ashouri R, Nakhaee N, Abbott PV, Gorjestani H. Effect of occlusal reduction on postoperative pain in teeth with irreversible pulpitis and mild tenderness to percussion. J Endod. 2013 Jan;39(1):1-5. doi: 10.1016/j.joen.2012.08.008. Epub 2012 Sep 29.

  PMID: 23228248 BACKGROUND

• Ahmed YE, Emara RS, Sarhan SM, El Boghdadi RM, El-Bayoumi MAA, El-Far HMM, Sabet NE, Abou El-Nasr HM, Gawdat SI, Amin SAW. Post-treatment endodontic pain following occlusal reduction in mandibular posterior teeth with symptomatic irreversible pulpitis and sensitivity to percussion: a single-centre randomized controlled trial. Int Endod J. 2020 Sep;53(9):1170-1180. doi: 10.1111/iej.13328. Epub 2020 Jun 15.

  PMID: 32418236 BACKGROUND

• Emara RS, Abou El Nasr HM, El Boghdadi RM. Evaluation of postoperative pain intensity following occlusal reduction in teeth associated with symptomatic irreversible pulpitis and symptomatic apical periodontitis: a randomized clinical study. Int Endod J. 2019 Mar;52(3):288-296. doi: 10.1111/iej.13012. Epub 2018 Sep 28.

  PMID: 30171777 BACKGROUND

• Rosenberg PA, Babick PJ, Schertzer L, Leung A. The effect of occlusal reduction on pain after endodontic instrumentation. J Endod. 1998 Jul;24(7):492-6. doi: 10.1016/S0099-2399(98)80054-X.

  PMID: 9693578 BACKGROUND

• Nguyen-Nhon D, Nagendrababu V, Pulikkotil SJ, Rossi-Fedele G. Effect of occlusal reduction on postendodontic pain: A systematic review and meta-analysis of randomised clinical trials. Aust Endod J. 2020 Aug;46(2):282-294. doi: 10.1111/aej.12380. Epub 2019 Oct 22.

  PMID: 31638301 BACKGROUND

• Sathorn C, Parashos P, Messer H. The prevalence of postoperative pain and flare-up in single- and multiple-visit endodontic treatment: a systematic review. Int Endod J. 2008 Feb;41(2):91-9. doi: 10.1111/j.1365-2591.2007.01316.x. Epub 2007 Oct 23.

  PMID: 17956561 BACKGROUND

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 5, 2025
• First Posted: May 1, 2025
• Study Start: August 3, 2020
• Primary Completion: January 29, 2021
• Study Completion: February 5, 2021
• Last Updated: May 1, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL

Locations

TU (1)