Feasibility and Preliminary Efficacy of a Group-based Telerehabilitation Program in People With Post-COVID-19 Sequelae (TEPCO).

NCT06952127 | Completed

• 2 other identifiers: 2023-667889
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study pilot randomized controlled study is to evaluate the feasibility of the study procedures and to compare the preliminary efficacy of a rehabilitation program given in a "remote" (telerehabilitation) or "face-to-face" model for adult patients who had confirmed SARS-CoV-2 infection and still have symptoms after eight weeks of infection. The main question it aims to answer is:

• Are the study procedures feasible?
• Will the two groups have similar results for the preliminary efficacy outcomes? Researchers will compare group telerehabilitation to a face-to-face group to see if it's comparable. Participants will:
• Take part in a 60-minute training session, 3 times a week in person or remotely
• Visit the clinic before starting the training program and after 8 weeks of training
• Keep a diary of their symptoms, if any

Conditions

Long COVID-19 Syndrome; Long COVID; Long COVID Syndrome

Keywords

telerehabilitation

Outcome Measures

Primary Outcomes (1)

• The feasibility of study procedures

  This will be evaluated by % of participants that accept to participate in the study (recruitment rate), % of participants who drop out or withdraw from a study (attrition rate), % completed session (adherence rate); number of adverse events and % of participants satisfaction.

  8 weeks

Secondary Outcomes (7)

• Exercise capacity

  8 weeks

• Walking capacity

  8 weeks

• Lower-limb endurance

  8 weeks

• Physical performance

  8 weeks

• Change in Independence in activities of daily living

  8 weeks

Study Arms (2)

Telerehabilitation group

EXPERIMENTAL

Rehabilitation program including cardiovascular, muscular and balance training and, if necessary, respiratory physiotherapy using the Teams platform supervised by a certified kinesiologist. The rehabilitation will be conducted 3 times a week for 8 weeks in group of 5 or 6 persons.

Other: Rehabilitation program

Face-to-face group

ACTIVE COMPARATOR

Rehabilitation program including cardiovascular, muscular and balance training and, if necessary, respiratory physiotherapy at the university kinesiology clinic supervised by a certified kinesiologist. The rehabilitation will be conducted 3 times a week for 8 weeks in group of 5 or 6 persons.

Other: Rehabilitation program

Interventions

Rehabilitation program OTHER

* 5-minute warm-up including easy global exercises * 5 resistance training exercises targeting upper and lower muscle groups * 30 secondes break between sets * Cooldown with breathing and stretching exercises

Face-to-face group; Telerehabilitation group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• adult patients (≥18 years)
• confirmed SARS-CoV-2 infection defined by positive polymerase chain reaction (PCR) testing and/or antigen test results
• referred to the pneumology clinic for a modified British Medical Research Council (mMRC) dyspnea score of 2-3 after a minimum of eight weeks of infection
• VO₂max of less than 80% of the predicted value
• receiving a medical prescription for rehabilitation following initial assessment by a pulmonologist
• being able to walk independently
• providing informed consent
• having a good internet connection (i.e., a minimum download speed of 4 Mbps and an upload speed of 4 Mbps)
• being in possession of a computer or tablet equipped with a camera enabling videoconferencing.

You may not qualify if:

• requiring in-hospital rehabilitation at discharge
• evidence of medical instability (i.e., moderate or severe cardiac disease, ischemic or severe hemorrhagic stroke, or neurodegenerative disease, unstable fracture)
• history of severe cognitive or mental impairment
• already enrolled in another rehabilitation program

Sponsors & Collaborators

• Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec: lead

Study Sites (1)

Centre hospitalier affilié universitaire régional

Trois-Rivières, Quebec, G8Z 3R9, Canada

Location

MeSH Terms

Conditions

Post-Acute COVID-19 Syndrome

Interventions

Rehabilitation

Condition Hierarchy (Ancestors)

COVID-19; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 24, 2025
• First Posted: April 30, 2025
• Study Start: April 7, 2023
• Primary Completion: March 29, 2024
• Study Completion: March 29, 2024
• Last Updated: April 30, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)